Roderic G Eckenhoff
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Explore the profile of Roderic G Eckenhoff including associated specialties, affiliations and a list of published articles.
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148
Citations
2942
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Recent Articles
1.
Bedell V, Dubey P, Datta R, Eckenhoff R, Bedell V
bioRxiv
. 2025 Jan;
PMID: 39763736
Anesthetic and sedative drugs are small compounds known to bind to hundreds of proteins. One intriguing binding partner of propofol is the kinesin motor domain, kif5A, a neuronal mitochondrial transport...
2.
Joseph T, Bu W, Haji-Ghassemi O, Chen Y, Woll K, Allen P, et al.
Br J Anaesth
. 2024 Sep;
133(5):1093-1100.
PMID: 39304470
Background: As the primary Ca release channel in skeletal muscle sarcoplasmic reticulum (SR), mutations in type 1 ryanodine receptor (RyR1) or its binding partners underlie a constellation of muscle disorders,...
3.
Koutsogiannaki S, Limratana P, Bu W, Maisat W, McKinstry-Wu A, Han X, et al.
Int Immunopharmacol
. 2024 Aug;
141:112975.
PMID: 39163686
Background: While a number of anesthetics has been shown potentially associated with neurotoxicity in the developing brain, dexmedetomidine, a drug that was rather recently introduced into the perioperative setting, is...
4.
Plasencia D, Rodgers L, Knighton A, Eckenhoff R, White E
Sci Rep
. 2024 Jul;
14(1):15943.
PMID: 38987614
Despite their frequent use across many clinical settings, general anesthetics are medications with lethal side effects and no reversal agents. A fluorinated analogue of propofol has previously been shown to...
5.
Plasencia D, Rodgers L, Knighton A, Eckenhoff R, White E
Res Sq
. 2024 Jan;
PMID: 38260679
Despite their frequent use across many clinical settings, general anesthetics are medications with lethal side effects and no reversal agents. A fluorinated analogue of propofol has previously been shown to...
6.
Joseph T, Bu W, Haji-Ghassemi O, Chen Y, Woll K, Allen P, et al.
bioRxiv
. 2024 Jan;
PMID: 38260485
As the primary Ca release channel in skeletal muscle sarcoplasmic reticulum (SR), mutations in the type 1 ryanodine receptor (RyR1) or its binding partners underlie a constellation of muscle disorders,...
7.
McKinstry-Wu A, Wasilczuk A, Dailey W, Eckenhoff R, Kelz M
J Neurosci
. 2023 Feb;
43(13):2338-2348.
PMID: 36849414
Photoaffinity ligands are best known as tools used to identify the specific binding sites of drugs to their molecular targets. However, photoaffinity ligands have the potential to further define critical...
8.
Vasunilashorn S, Lunardi N, Newman J, Crosby G, Acker L, Abel T, et al.
Alzheimers Dement
. 2023 Feb;
19(5):2150-2174.
PMID: 36799408
Delirium is a common, morbid, and costly syndrome that is closely linked to Alzheimer's disease (AD) and AD-related dementias (ADRD) as a risk factor and outcome. Human studies of delirium...
9.
Koutsogiannaki S, Bu W, Maisat W, Manzor M, Zhang Z, Ohto U, et al.
FASEB J
. 2022 Jul;
36(8):e22481.
PMID: 35899460
Sedatives/anesthetics are important medical tools to facilitate medical care and increase patients' comfort. Increasingly, there is recognition that sedatives/anesthetics can modulate immune functions. Toll-like receptors (TLRs) are major pattern recognition...
10.
Xu D, DeYoung T, Kondoleon N, Eckenhoff R, Eckenhoff M
Anesth Analg
. 2021 Oct;
133(5):1140-1151.
PMID: 34673725
Background: Parkinson disease is a chronic and progressive movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The causes of Parkinson disease are...