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Chun-Lin Zhuang

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Citations 204
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Recent Articles
1.
Zhang J, Jia X, Cao Q, Chen Y, Tong J, Lu G, et al.
ACS Chem Neurosci . 2023 Aug; 14(17):2995-3012. PMID: 37579022
Ferroptosis is increasingly being recognized as a key element in the pathogenesis of diverse diseases. Recent studies have highlighted the intricate links between iron metabolism and neurodegenerative disorders. Emerging evidence...
2.
He X, Wang F, Suo X, Gu M, Wang J, Xu C, et al.
Br J Pharmacol . 2023 May; 180(20):2641-2660. PMID: 37248964
Background And Purpose: Necroptosis plays an essential role in acute kidney injury and is mediated by receptor-interacting protein kinase 1 (RIPK1), receptor-interacting protein kinase 3 (RIPK3), and mixed lineage kinase...
3.
Ling Z, Lv Q, Li J, Lu R, Chen L, Xu W, et al.
Inflammation . 2023 May; 46(5):1796-1809. PMID: 37227549
Excessive inflammatory response is a critical pathogenic factor for the tissue damage and organ failure caused by systemic inflammatory response syndrome (SIRS) and sepsis. In recent years, drugs targeting RIPK1...
4.
Wu Y, Tang J, Zhang W, Zhuang C, Shi Y
RSC Adv . 2022 Dec; 12(54):35242-35259. PMID: 36540233
Cannabinoid receptors belong to the large family of G-protein-coupled receptors, which can be divided into two receptor types, cannabinoid receptor type-1 (CB1) and cannabinoid receptor type-2 (CB2). Marinol, Cesamet and...
5.
Tong J, Lan X, Zhang Z, Liu Y, Sun D, Wang X, et al.
Acta Pharmacol Sin . 2022 Nov; 44(5):1014-1028. PMID: 36323829
Ferroptosis is a new form of regulated cell death characterized by excessive iron accumulation and uncontrollable lipid peroxidation. The role of ferroptosis in metabolic dysfunction-associated fatty liver disease (MAFLD) is...
6.
Shi Y, Wu Y, Yu J, Zhang W, Zhuang C
RSC Adv . 2022 Apr; 11(4):2359-2376. PMID: 35424149
A DNA-encoded library is a collection of small molecules covalently linked to DNA that has unique information about the identity and the structure of each library member. A DNA-encoded chemical...
7.
Zhang C, Tu Y, Sun X, Chen D, Zhang W, Zhuang C, et al.
Front Immunol . 2022 Mar; 13:856327. PMID: 35296098
Coronavirus Disease 2019 (COVID-19) infected by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been declared a public health emergency of international concerns. Cytokine storm syndrome (CSS) is a critical clinical...
8.
Su L, Tu Y, Kong D, Chen D, Zhang C, Zhang W, et al.
Biomed Pharmacother . 2020 Aug; 131:110643. PMID: 32846329
Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2) has been widely spread in the world with a high mortality. Cytokine storm syndrome (CSS) and acute...
9.
Li T, Pannecouque C, De Clercq E, Zhuang C, Chen F
Molecules . 2020 Apr; 25(7). PMID: 32235557
Scaffold hopping is a frequently-used strategy in the development of non-nucleoside reverse transcriptase inhibitors. Herein, CH(CN)-DAPYs were designed by hopping the cyano-methylene linker of our previous published CH(CN)-DABOs onto the...
10.
Liu D, Sun Y, Kurtan T, Mandi A, Tang H, Li J, et al.
J Nat Prod . 2019 Apr; 82(5):1274-1282. PMID: 30978020
Three new compounds (9-11) were isolated together with eight known analogues from the fungus Pseudallescheria boydii associated with the South China Sea soft coral Sinularia sandensis. The structures of the...