Christopher V E Wright
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Explore the profile of Christopher V E Wright including associated specialties, affiliations and a list of published articles.
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92
Citations
7059
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Recent Articles
1.
Saunders D, Hart N, Pan F, Reihsmann C, Hopkirk A, Izmaylov N, et al.
bioRxiv
. 2025 Jan;
PMID: 39763926
Human endocrine cell differentiation and islet morphogenesis play critical roles in determining islet cell mass and function, but the events and timeline of these processes are incompletely defined. To better...
2.
Trinh L, Finnel R, Osipovich A, Musselman J, Sampson L, Wright C, et al.
Development
. 2025 Jan;
152(2).
PMID: 39745200
Expression of SRY-box transcription factor 17 (Sox17) in the endodermal region caudal to the hepatic diverticulum during late gastrulation is necessary for hepato-pancreato-biliary system formation. Analysis of an allelic series...
3.
Shirazi S, Negretti N, Jetter C, Sharkey A, Garg S, Kapp M, et al.
bioRxiv
. 2024 Sep;
PMID: 39253423
Lung injury in preterm infants leads to structural and functional respiratory deficits, with a risk for bronchopulmonary dysplasia (BPD) that in its most severe form is accompanied by pulmonary hypertension...
4.
Sohn Y, Flores Semyonov B, El-Mekkoussi H, Wright C, Kaestner K, Choi E, et al.
Cell Mol Gastroenterol Hepatol
. 2024 Apr;
18(2):101347.
PMID: 38670488
Background & Aim: Telocytes, a recently identified type of subepithelial interstitial cell, have garnered attention for their potential roles in tissue homeostasis and repair. However, their contribution to gastric metaplasia...
5.
Trinh L, Osipovich A, Liu B, Shrestha S, Cartailler J, Wright C, et al.
Stem Cells
. 2023 Apr;
41(6):643-657.
PMID: 37085274
During early embryogenesis, the transcription factor SOX17 contributes to hepato-pancreato-biliary system formation and vascular-hematopoietic emergence. To better understand Sox17 function in the developing endoderm and endothelium, we developed a dual-color...
6.
Hu R, Walker E, Huang C, Xu Y, Weng C, Erickson G, et al.
Dev Cell
. 2020 Jun;
53(6):754.
PMID: 32574594
No abstract available.
7.
Hu R, Walker E, Huang C, Xu Y, Weng C, Erickson G, et al.
Dev Cell
. 2020 May;
53(4):390-405.e10.
PMID: 32359405
Although cellular stress response is important for maintaining function and survival, overactivation of late-stage stress effectors cause dysfunction and death. We show that the myelin transcription factors (TFs) Myt1 (Nzf2),...
8.
Yang X, Graff S, Heiser C, Ho K, Chen B, Simmons A, et al.
Diabetes
. 2020 Apr;
69(6):1219-1231.
PMID: 32245798
Swi-independent 3a and 3b (Sin3a and Sin3b) are paralogous transcriptional coregulators that direct cellular differentiation, survival, and function. Here, we report that mouse Sin3a and Sin3b are coproduced in most...
9.
Baeyens L, Lemper M, Leuckx G, De Groef S, Bonfanti P, Stange G, et al.
Nat Biotechnol
. 2020 Feb;
38(3):374.
PMID: 32066957
This article has been retracted; see accompanying Retraction Note, which can be accessed via a link at the top of the paper.
10.
Krah N, Narayanan S, Yugawa D, Straley J, Wright C, MacDonald R, et al.
Dev Cell
. 2019 Aug;
50(6):744-754.e4.
PMID: 31422917
Activating mutations in Kras are nearly ubiquitous in human pancreatic cancer and initiate precancerous pancreatic intraepithelial neoplasia (PanINs) when induced in mouse acinar cells. PanINs normally take months to form...