Guoqiang Gu
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Explore the profile of Guoqiang Gu including associated specialties, affiliations and a list of published articles.
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Articles
126
Citations
3749
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Recent Articles
1.
Hu R, Yagan M, Wang Y, Tong X, Doss T, Liu J, et al.
bioRxiv
. 2025 Mar;
PMID: 40060649
Highlights: MYT1-KD compromises human β-cell survival but not insulin secretionMYT3-KD compromises human β-cell insulin secretion but not survivalMYT3-KD compromises human β-cell viability in obesityMYT1 and MYT3 regulate overlapping but distinct...
2.
Zhang P, Zhan T, Gu G, Li C, Zhang Y, Yang H
Annu Int Conf IEEE Eng Med Biol Soc
. 2025 Mar;
2024:1-4.
PMID: 40031492
The advancement of scattering-based single-particle tracking (S-SPT) has revolutionized label-free detection and characterization of nanoscopic objects, promising diverse analytical applications. Nevertheless, its widespread adoption has been impeded by the high...
3.
Xie R, Shen J, Zhou L, Lu L, Zhi A, Sun D, et al.
ACS Sens
. 2025 Feb;
PMID: 39927898
Bacterial infections often lead to severe health consequences owing to their ability to infiltrate multiple anatomical sites, including the bloodstream, respiratory tract, and digestive tract, posing substantial diagnostic and therapeutic...
4.
Hu R, Zhu X, Yuan M, Ho K, Kaverina I, Gu G
PLoS One
. 2025 Feb;
20(2):e0314639.
PMID: 39913355
[This corrects the article DOI: 10.1371/journal.pone.0241939.].
5.
Yagan M, Najam S, Hu R, Wang Y, Dickerson M, Dadi P, et al.
Diabetes
. 2025 Feb;
PMID: 39899446
Glucolipotoxicity, caused by combined hyperglycemia and hyperlipidemia, results in β-cell failure and type 2 diabetes via cellular stress-related mechanisms. Activating transcription factor 4 (Atf4) is an essential effector of stress...
6.
Fye M, Sangowdar P, Jaythilake A, Noguchi P, Gu G, Kaverina I
bioRxiv
. 2024 Nov;
PMID: 39553950
To maintain normal blood glucose levels, pancreatic beta cells secrete insulin into the bloodstream at specialized regions at the cell periphery, often called secretion hot spots. While many secretory machinery...
7.
Zhi Y, Duan Y, Zhang Y, Hu H, Hu F, Wang P, et al.
Eur J Pharmacol
. 2024 Nov;
985:177085.
PMID: 39486770
Pathological cardiac hypertrophy is an independent risk factor for heart failure. Currently, clinical treatments offer limited effectiveness, and both mortality and morbidity from cardiac hypertrophy and heart failure continue to...
8.
Ho K, Barmaver S, Hu R, Yagan M, Ahmed H, Kaverina I, et al.
bioRxiv
. 2024 Nov;
PMID: 39484371
Highlights: Gcg sensitizes glucose-induced MT remodeling in mouse and human β cellsMT density in single islets anti-correlates with α/β cell ratioGSIS levels in single islets positively correlate with α/β cell...
9.
Tong X, Yagan M, Hu R, Nevills S, Doss T, Stein R, et al.
Diabetes
. 2024 Jul;
73(10):1662-1672.
PMID: 39058602
Article Highlights:
10.
Yagan M, Najam S, Hu R, Wang Y, Dadi P, Xu Y, et al.
bioRxiv
. 2024 Jul;
PMID: 39005465
Highlights: Atf4 is dispensable in β-cells in young miceAtf4 protects β-cells under high glucoseAtf4 exacerbate fatty acid-induced β-cell defectsAtf4 activates translation but depresses lipid-metabolism.