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Christopher Mulligan

Explore the profile of Christopher Mulligan including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 387
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Recent Articles
11.
Vergara-Jaque A, Fenollar-Ferrer C, Mulligan C, Mindell J, Forrest L
J Gen Physiol . 2015 Oct; 146(5):423-34. PMID: 26503722
Membrane transporter proteins catalyze the passage of a broad range of solutes across cell membranes, allowing the uptake and efflux of crucial compounds. Because of the difficulty of expressing, purifying,...
12.
Mulligan C, Salisbury E, Tschuchnigg M, Moradi P, Matthews A, Warrier S
Plast Reconstr Surg Glob Open . 2014 Nov; 2(10):e238. PMID: 25426355
Anaplastic large cell lymphoma of the breast is a rare malignancy associated with prosthetic breast implants. We present a case of a woman with no prior history of breast implants...
13.
Mulligan C, Fitzgerald G, Wang D, Mindell J
J Gen Physiol . 2014 May; 143(6):745-59. PMID: 24821967
The SLC13 transporter family, whose members play key physiological roles in the regulation of fatty acid synthesis, adiposity, insulin resistance, and other processes, catalyzes the transport of Krebs cycle intermediates...
14.
Mulligan C, Mindell J
J Biol Chem . 2013 Oct; 288(49):35266-76. PMID: 24155238
Secondary transporters in the excitatory amino acid transporter family terminate glutamatergic synaptic transmission by catalyzing Na(+)-dependent removal of glutamate from the synaptic cleft. Recent structural studies of the aspartate-specific archaeal...
15.
Mulligan C, Leech A, Kelly D, Thomas G
J Biol Chem . 2011 Dec; 287(5):3598-608. PMID: 22167185
Tripartite ATP-independent periplasmic (TRAP) transporters are widespread in bacteria but poorly characterized. They contain three subunits, a small membrane protein, a large membrane protein, and a substrate-binding protein (SBP). Although...
16.
Mulligan C, Fischer M, Thomas G
FEMS Microbiol Rev . 2010 Jun; 35(1):68-86. PMID: 20584082
The tripartite ATP-independent periplasmic (TRAP) transporters are the best-studied family of substrate-binding protein (SBP)-dependent secondary transporters and are ubiquitous in prokaryotes, but absent from eukaryotes. They are comprised of an...
17.
Mulligan C, Geertsma E, Severi E, Kelly D, Poolman B, Thomas G
Proc Natl Acad Sci U S A . 2009 Jan; 106(6):1778-83. PMID: 19179287
Substrate-binding protein-dependent secondary transporters are widespread in prokaryotes and are represented most frequently by members of the tripartite ATP-independent periplasmic (TRAP) transporter family. Here, we report the membrane reconstitution of...
18.
Mulligan C, Kelly D, Thomas G
J Mol Microbiol Biotechnol . 2007 Jun; 12(3-4):218-26. PMID: 17587870
Tripartite ATP-independent periplasmic (TRAP) transporters are a family of extracytoplasmic solute receptor-dependent secondary transporters that are widespread in the prokaryotic world but which have not been extensively studied. Here, we...
19.
Espinal A, Quijano J, Hunt C, Lorenzo R, Mulligan C, Sampson M, et al.
Mol Biochem Parasitol . 2006 Dec; 151(2):224-8. PMID: 17140676
No abstract available.
20.
Muller A, Severi E, Mulligan C, Watts A, Kelly D, Wilson K, et al.
J Biol Chem . 2006 May; 281(31):22212-22222. PMID: 16702222
Extracytoplasmic solute receptors (ESRs) are important components of solute uptake systems in bacteria, having been studied extensively as parts of ATP binding cassette transporters. Herein we report the first crystal...