Christopher Moth
Overview
Explore the profile of Christopher Moth including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
8
Followers
0
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Recent Articles
1.
Grunin M, de Jong S, Palmer E, Jin B, Rinker D, Moth C, et al.
medRxiv
. 2023 Sep;
PMID: 37693462
Purpose: Genetic variants in complement genes are associated with age-related macular degeneration (AMD). However, many rare variants have been identified in these genes, but have an unknown significance, and their...
2.
Grunin M, Palmer E, de Jong S, Jin B, Rinker D, Moth C, et al.
Adv Exp Med Biol
. 2023 Jul;
1415:157-163.
PMID: 37440029
Protein function can be impacted by changes in protein structure stability, but determining which change has impact is complex. Stability can be affected by a large change in the tertiary...
3.
Gadbery J, Abraham A, Needle C, Moth C, Sheehan J, Capra J, et al.
Protein Sci
. 2020 Apr;
29(6):1535-1549.
PMID: 32285480
Genetic variation in the membrane trafficking adapter protein complex 4 (AP-4) can result in pathogenic neurological phenotypes including microencephaly, spastic paraplegias, epilepsy, and other developmental defects. We lack molecular mechanisms...