William S Bush
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Explore the profile of William S Bush including associated specialties, affiliations and a list of published articles.
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170
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4777
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Recent Articles
1.
Durant A, Mukherjee S, Lee M, Choi S, Scollard P, Klinedinst B, et al.
medRxiv
. 2025 Jan;
PMID: 39830268
Importance: "SuperAgers" are oldest-old adults (ages 80+) whose memory performance resembles that of adults in their 50s to mid-60s. Factors underlying their exemplary memory are underexplored in large, racially diverse...
2.
Gonzalez-Vicente A, Crawford D, Bush W, Wu Z, Bruggeman L, Nair V, et al.
medRxiv
. 2025 Jan;
PMID: 39830251
The disproportionate risk for idiopathic proteinuric podocytopathies in Black people is explained, in part, by the presence of two risk alleles (G1 or G2) in the gene. The pathogenic mechanisms...
3.
Leung Y, Lee W, Kuzma A, Nicaretta H, Valladares O, Gangadharan P, et al.
medRxiv
. 2024 Dec;
PMID: 39677464
The Alzheimer's Disease Sequencing Project (ADSP) is a national initiative to understand the genetic architecture of Alzheimer's Disease and Related Dementias (AD/ADRD) by sequencing whole genomes of affected participants and...
4.
Gorski M, Grunin M, Herold J, Frohlich B, Behr M, Wheeler N, et al.
medRxiv
. 2024 Nov;
PMID: 39606372
Age-related macular degeneration (AMD) is a leading cause of blindness with $344 billion dollars global costs. In 2016, the International Age-related Macular Degeneration Genomics Consortium devised genomic data on ∼50,000...
5.
Liu R, Qiao X, Shi Y, Peterson C, Bush W, Cominelli F, et al.
Comput Struct Biotechnol J
. 2024 Nov;
23:3859-3868.
PMID: 39554614
As next-generation sequencing technologies advance rapidly and the cost of metagenomic sequencing continues to decrease, researchers now face an unprecedented volume of microbiome data. This surge has stimulated the development...
6.
Cruz-Gonzalez S, Gu E, Gomez L, Mews M, Vance J, Cuccaro M, et al.
bioRxiv
. 2024 Oct;
PMID: 39464059
Epigenetic clocks that quantify rates of aging from DNA methylation patterns across the genome have emerged as a potential biomarker for risk of age-related diseases, like Alzheimer's disease (AD), and...
7.
Tong T, Zhu C, Farrell J, Khurshid Z, Martin E, Pericak-Vance M, et al.
Alzheimers Res Ther
. 2024 Oct;
16(1):234.
PMID: 39444005
Background: Blood-derived mitochondrial DNA copy number (mtDNA-CN) is a proxy measurement of mitochondrial function in the peripheral and central systems. Abnormal mtDNA-CN not only indicates impaired mtDNA replication and transcription...
8.
Lee W, Choi S, Shea M, Cheng P, Dombroski B, Pitsillides A, et al.
Alzheimers Dement
. 2024 Oct;
20(12):8470-8483.
PMID: 39428839
Introduction: Alzheimer's disease (AD) is a common disorder of the elderly that is both highly heritable and genetically heterogeneous. Methods: We investigated the association of AD with both common variants...
9.
Kaur H, Alluri R, Wu K, Kalayjian R, Bush W, Palella F, et al.
Antioxidants (Basel)
. 2024 Sep;
13(9).
PMID: 39334701
Ferroptosis is implicated in viral neuropathogenesis and may underlie HIV-associated neurocognitive impairment (NCI). Emerging data also suggest differences in brain iron transport by sex. We hypothesized that circulating ferritins that...
10.
Ciesielski T, Tosto G, Durodoye R, Rajabali F, Akinyemi R, Byrd G, et al.
medRxiv
. 2024 Aug;
PMID: 39148832
Introduction: Clinical and genetic studies have implicated lipid dysfunction in Alzheimer Disease (AD) pathogenesis. However, lipid consumption at the individual-level does not vary greatly within most cohorts, and multiple lipids...