Anneke I den Hollander
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Explore the profile of Anneke I den Hollander including associated specialties, affiliations and a list of published articles.
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275
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10617
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Recent Articles
1.
Ratnapriya R, Grassman F, Chen R, Hewitt A, Du J, Saban D, et al.
Exp Eye Res
. 2025 Mar;
:110344.
PMID: 40089136
Genome-wide association studies have been remarkably successful in identifying genetic variants associated with age-related macular degeneration (AMD), demonstrating a strong genetic component largely driven by common variants. However, progress in...
2.
Brink S, ten Brink S, Koolen L, Klaver C, Bakker R, den Hollander A, et al.
Stem Cell Reports
. 2025 Jan;
20(1):102385.
PMID: 39753135
Complement factor H (CFH) common genetic variants have been associated with age-related macular degeneration (AMD). While most previous in vitro RPE studies focused on the common p.His402Tyr CFH variant, we...
3.
Farashi S, Abbott C, Ansell B, Wu Z, Altay L, Arnon E, et al.
medRxiv
. 2024 Oct;
PMID: 39399049
Age-related macular degeneration (AMD) is a multifactorial retinal disease with a large genetic risk contribution. Reticular pseudodrusen (RPD) is a sub-phenotype of AMD with a high risk of progression to...
4.
Hallak J, Abbasi A, Goldberg R, Modi Y, Zhao C, Jing Y, et al.
JAMA Ophthalmol
. 2024 Jul;
142(8):750-758.
PMID: 38990568
Importance: The involvement of chronic inflammation in the pathogenesis of age-related macular degeneration (AMD) opens therapeutic possibilities to AMD management. Objective: To determine whether Janus kinase inhibitors (JAKis) are associated...
5.
Karjalainen M, Karthikeyan S, Oliver-Williams C, Sliz E, Allara E, Fung W, et al.
Nature
. 2024 Mar;
628(8006):130-138.
PMID: 38448586
Genome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism. This detailed knowledge of the genetic determinants of systemic metabolism has been...
6.
Govers B, van Huet R, El Kandoussi M, den Hollander A, Keijser S, Klevering B
Acta Ophthalmol
. 2023 Dec;
102(5):513-520.
PMID: 38146841
Purpose: To describe clinical characteristics and management in a large cohort of patients with retinal detachment due to a giant retinal tear (GRT). Methods: We performed a retrospective cohort study...
7.
Acar I, Galesloot T, Luhmann U, Fauser S, Gayan J, den Hollander A, et al.
Invest Ophthalmol Vis Sci
. 2023 Nov;
64(14):24.
PMID: 37975850
Purpose: To identify associations of common, low-frequency, and rare variants with advanced age-related macular degeneration (AMD) using whole genome sequencing (WGS). Methods: WGS data were obtained for 2123 advanced AMD...
8.
Riley-Gillis B, Huh H, Shen J, den Hollander A
Acta Ophthalmol
. 2023 Nov;
101(8):869-880.
PMID: 37933607
Geographic atrophy (GA) is characterized by atrophy of the retina, retinal pigment epithelium and choriocapillaris, causing a gradual loss of vision over time. Treatment options to prevent initiation or progression...
9.
Grunin M, de Jong S, Palmer E, Jin B, Rinker D, Moth C, et al.
medRxiv
. 2023 Sep;
PMID: 37693462
Purpose: Genetic variants in complement genes are associated with age-related macular degeneration (AMD). However, many rare variants have been identified in these genes, but have an unknown significance, and their...
10.
Grunin M, Palmer E, de Jong S, Jin B, Rinker D, Moth C, et al.
Adv Exp Med Biol
. 2023 Jul;
1415:157-163.
PMID: 37440029
Protein function can be impacted by changes in protein structure stability, but determining which change has impact is complex. Stability can be affected by a large change in the tertiary...