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Christopher J Porter

Explore the profile of Christopher J Porter including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
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Recent Articles
11.
Liang L, Coudiere-Morrison L, Tatari N, Stromecki M, Fresnoza A, Porter C, et al.
Cancer Res . 2018 Jun; 78(16):4745-4759. PMID: 29930101
The extensive heterogeneity both between and within the medulloblastoma subgroups underscores a critical need for variant-specific biomarkers and therapeutic strategies. We previously identified a role for the CD271/p75 neurotrophin receptor...
12.
Manias Rothberg J, Maganti H, Jrade H, Porter C, Palidwor G, Cafariello C, et al.
Cell Discov . 2018 May; 4:21. PMID: 29736258
Polycomb repressive complex 2 (PRC2) accessory proteins play substoichiometric, tissue-specific roles to recruit PRC2 to specific genomic loci or increase enzymatic activity, while PRC2 core proteins are required for complex...
13.
Benyoucef A, Palii C, Wang C, Porter C, Chu A, Dai F, et al.
Genes Dev . 2016 Mar; 30(5):508-21. PMID: 26944678
T-cell acute lymphoblastic leukemia (T-ALL) is a heterogeneous group of hematological tumors composed of distinct subtypes that vary in their genetic abnormalities, gene expression signatures, and prognoses. However, it remains...
14.
Ramachandran P, Palidwor G, Porter C, Perkins T
Bioinformatics . 2013 Jan; 29(4):444-50. PMID: 23300135
Motivation: Reliable estimation of the mean fragment length for next-generation short-read sequencing data is an important step in next-generation sequencing analysis pipelines, most notably because of its impact on the...
15.
Soleimani V, Punch V, Kawabe Y, Jones A, Palidwor G, Porter C, et al.
Dev Cell . 2012 May; 22(6):1208-20. PMID: 22609161
Pax3 and Pax7 regulate stem cell function in skeletal myogenesis. However, molecular insight into their distinct roles has remained elusive. Using gene expression data combined with genome-wide binding-site analysis, we...
16.
Sandie R, Palidwor G, Huska M, Porter C, Krzyzanowski P, Muro E, et al.
BMC Res Notes . 2009 Mar; 2:39. PMID: 19284540
Background: Currently one of the largest online repositories for human and mouse stem cell gene expression data, StemBase was first designed as a simple web-interface to DNA microarray data generated...
17.
Porter C, Palidwor G, Sandie R, Krzyzanowski P, Muro E, Perez-Iratxeta C, et al.
Methods Mol Biol . 2008 May; 407:137-48. PMID: 18453254
StemBase is a database of gene expression data obtained from stem cells and derivatives mainly from mouse and human using DNA microarrays and Serial Analysis of Gene Expression. Here, we...
18.
McCann J, Muro E, Palmer C, Palidwor G, Porter C, Andrade-Navarro M, et al.
BMC Genomics . 2007 Sep; 8:322. PMID: 17868463
Background: SNP microarrays are designed to genotype Single Nucleotide Polymorphisms (SNPs). These microarrays report hybridization of DNA fragments and therefore can be used for the purpose of detecting genomic fragments....
19.
Hailesellasse Sene K, Porter C, Palidwor G, Perez-Iratxeta C, Muro E, Campbell P, et al.
BMC Genomics . 2007 Mar; 8:85. PMID: 17394647
Background: Little is known about the genes that drive embryonic stem cell differentiation. However, such knowledge is necessary if we are to exploit the therapeutic potential of stem cells. To...
20.
Bonnet S, Archer S, Allalunis-Turner J, Haromy A, Beaulieu C, Thompson R, et al.
Cancer Cell . 2007 Jan; 11(1):37-51. PMID: 17222789
The unique metabolic profile of cancer (aerobic glycolysis) might confer apoptosis resistance and be therapeutically targeted. Compared to normal cells, several human cancers have high mitochondrial membrane potential (DeltaPsim) and...