Christopher I Murray
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Explore the profile of Christopher I Murray including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
811
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Recent Articles
1.
Champagne A, Coverdale N, Skinner C, Schwarz B, Glikstein R, Melkus G, et al.
Brain Inj
. 2024 Dec;
:1-9.
PMID: 39729051
Objective: The purpose of this study was to determine whether gray matter volume and diffusion-based metrics in associated white matter changed in breachers who had neuroimaging performed at two timepoints....
2.
Fu Q, Vegesna M, Sundararaman N, Damoc E, Arrey T, Pashkova A, et al.
Angew Chem Int Ed Engl
. 2024 Oct;
63(52):e202409446.
PMID: 39432331
Clinical biomarker development has been stymied by inaccurate protein quantification from mass spectrometry (MS) discovery data and a prolonged validation process. To mitigate these issues, we created the Targeted Extraction...
3.
Karpov O, Stotland A, Raedschelders K, Chazarin B, Ai L, Murray C, et al.
Physiol Rev
. 2024 Feb;
104(3):931-982.
PMID: 38300522
Mass spectrometry-based proteomics is a sophisticated identification tool specializing in portraying protein dynamics at a molecular level. Proteomics provides biologists with a snapshot of context-dependent protein and proteoform expression, structural...
4.
S-Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S-Nitrosylation and Preeclampsia
Kulandavelu S, Dulce R, Murray C, Bellio M, Fritsch J, Kanashiro-Takeuchi R, et al.
J Am Heart Assoc
. 2022 Feb;
11(5):e024008.
PMID: 35191317
Background Preeclampsia, a leading cause of maternal and fetal mortality and morbidity, is characterized by an increase in S-nitrosylated proteins and reactive oxygen species, suggesting a pathophysiologic role for dysregulation...
5.
Fu Q, Murray C, Karpov O, Van Eyk J
Mass Spectrom Rev
. 2021 Nov;
42(2):873-886.
PMID: 34786750
Sample preparation for mass spectrometry-based proteomics has many tedious and time-consuming steps that can introduce analytical errors. In particular, the steps around the proteolytic digestion of protein samples are prone...
6.
Ardle A, Binek A, Moradian A, Chazarin Orgel B, Rivas A, Washington K, et al.
Clin Chem
. 2021 Oct;
68(3):450-460.
PMID: 34687543
Background: Accurate discovery assay workflows are critical for identifying authentic circulating protein biomarkers in diverse blood matrices. Maximizing the commonalities in the proteomic workflows between different biofluids simplifies the approach...
7.
Champagne A, Coverdale N, Ross A, Chen Y, Murray C, Dubowitz D, et al.
Neuroimage Clin
. 2020 Feb;
26:102204.
PMID: 32058317
Blood oxygenation level dependent (BOLD) resting-state functional magnetic resonance imaging (rs-fMRI) may serve as a sensitive marker to identify possible changes in the architecture of large-scale networks following mild traumatic...
8.
Westhoff M, Eldstrom J, Murray C, Thompson E, Fedida D
Proc Natl Acad Sci U S A
. 2019 Mar;
116(16):7879-7888.
PMID: 30918124
The current has an established role in cardiac action potential repolarization, and provides a repolarization reserve at times of stress. The underlying channels are formed from tetramers of KCNQ1 along...
9.
Fert-Bober J, Murray C, Parker S, Van Eyk J
Circ Res
. 2018 Apr;
122(9):1221-1237.
PMID: 29700069
There is an exponential increase in biological complexity as initial gene transcripts are spliced, translated into amino acid sequence, and post-translationally modified. Each protein can exist as multiple chemical or...
10.
Chung H, Murray C, Van Eyk J
Methods Mol Biol
. 2018 Mar;
1747:89-101.
PMID: 29600453
S-nitrosylation (or S-nitrosation, SNO) is an oxidative posttranslational modification to the thiol group of a cysteine amino acid residue. There are several methods to detect SNO modifications, mostly based on...