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Christopher E Randolph

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Articles 12
Citations 74
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Recent Articles
1.
Gai D, Caviness P, Lazarenko O, Chen J, Randolph C, Zhang Z, et al.
Cancers (Basel) . 2025 Mar; 17(5). PMID: 40075680
Multiple myeloma (MM) is a malignancy of terminally differentiated B-cells that is localized primarily in the bone marrow (BM) but also can be present in peripheral blood and tissue/organs [...].
2.
Liu Z, Tsai T, Zuo B, Howe S, Farrar J, Randolph C, et al.
J Anim Sci Biotechnol . 2025 Jan; 16(1):6. PMID: 39762999
Background: Sow longevity and reproductivity are essential in the modern swine industry. Although many studies have focused on the genetic and genomic factors for selection, little is known about the...
3.
Hakkak R, Korourian S, Li W, Spray B, Twaddle N, Randolph C, et al.
Front Nutr . 2024 Nov; 11:1487859. PMID: 39529929
Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major public health concern that is exacerbated by the obesity pandemic. Dietary interventions have the potential to alleviate obesity-associated MASLD through...
4.
Hong A, Piva M, Liu S, Hugo W, Lomeli S, Zoete V, et al.
Cancer Discov . 2024 Jul; 14(7):1357. PMID: 38946326
No abstract available.
5.
Gai D, Caviness P, Lazarenko O, Chen J, Randolph C, Zhang Z, et al.
Res Sq . 2024 May; PMID: 38766009
In multiple myeloma (MM), increased osteoclast differentiation leads to the formation of osteolytic lesions in most MM patients. Bisphosphonates, such as zoledronic acid (ZA), are used to ameliorate bone resorption,...
6.
Piccolo B, Graham J, Tabor-Simecka L, Randolph C, Moody B, Robeson M, et al.
BMJ Open Diabetes Res Care . 2024 Mar; 12(2). PMID: 38453236
Introduction: Colonocyte oxidation of bacterial-derived butyrate has been reported to maintain synergistic obligate anaerobe populations by reducing colonocyte oxygen levels; however, it is not known whether this process is disrupted...
7.
Caviness P, Lazarenko O, Blackburn M, Chen J, Randolph C, Zabaleta J, et al.
J Nutr Biochem . 2024 Feb; 127:109601. PMID: 38367948
Phenolic acids, such as hippuric acid (HA) and 3-(3-hydroxyphenyl) propionic acid (3-3-PPA), can be produced from microbiome digestion of polyphenols. Previously it was found that HA and 3-3-PPA facilitate bone...
8.
Chen J, Lazarenko O, Blackburn M, Chen J, Randolph C, Zabaleta J, et al.
Commun Biol . 2022 Jun; 5(1):583. PMID: 35701603
Tightly regulated and cell-specific NADPH-oxidases (Nox) represent one of the major sources of reactive oxygen species (ROS) signaling molecules that are involved in tissue development and stem cell self-renewal. We...
9.
Piccolo B, Graham J, Kang P, Randolph C, Shankar K, Yeruva L, et al.
Physiol Rep . 2021 Nov; 9(22):e15102. PMID: 34806320
Deterioration in glucose homeostasis has been associated with intestinal dysbiosis, but it is not known how metabolic dysregulation alters the gastrointestinal environment. We investigated how the progression of diabetes alters...
10.
Li M, Lyu C, Huang M, Do C, Tycko B, Lupo P, et al.
BMC Genom Data . 2021 Jun; 22(1):20. PMID: 34112112
Background: Most congenital heart defects (CHDs) result from complex interactions among genetic susceptibilities, epigenetic modifications, and maternal environmental exposures. Characterizing the complex relationship between genetic, epigenetic, and transcriptomic variation will...