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Hans-Rudolf Berthoud

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Articles 123
Citations 6109
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Recent Articles
1.
Francois M, Kaiser L, He Y, Xu Y, Salbaum J, Yu S, et al.
Metabolism . 2024 Dec; 163:156100. PMID: 39672257
The dorsomedial hypothalamus (DMH) receives inputs from the preoptic area (POA), where ambient temperature mediates physiological adaptations of energy expenditure and food intake. Warm-activated POA neurons suppress energy expenditure via...
2.
Khan M, Kim S, Ross R, Corpodean F, Spann R, Albarado D, et al.
Mol Metab . 2024 Nov; 91:102068. PMID: 39571902
Objective: Dietary protein restriction induces adaptive changes in food preference, increasing protein consumption over carbohydrates or fat. We investigated whether motivation and reward signaling underpin these preferences. Methods And Results:...
3.
Munzberg H, Heymsfield S, Berthoud H, Morrison C
Metabolism . 2024 Sep; 161:156026. PMID: 39245434
The cloning of leptin 30 years ago in 1994 was an important milestone in obesity research. Prior to the discovery of leptin, obesity was stigmatized as a condition caused by...
4.
Khan M, Kim S, Ross R, Corpodean F, Spann R, Albarado D, et al.
bioRxiv . 2024 May; PMID: 38798313
Dietary protein restriction induces adaptive changes in food preference, increasing protein consumption over carbohydrates or fat. We investigated whether motivation and reward signaling underpin these preferences. In an operant task,...
5.
Kim S, Spann R, Khan M, Berthoud H, Munzberg H, Albaugh V, et al.
Neuropharmacology . 2024 May; 255:110010. PMID: 38797244
Free-feeding animals navigate complex nutritional landscapes in which food availability, cost, and nutritional value can vary markedly. Animals have thus developed neural mechanisms that enable the detection of nutrient restriction,...
6.
Berthoud H, Munzberg H, Morrison C, Neuhuber W
Auton Neurosci . 2024 Apr; 253:103174. PMID: 38579493
The liver is a large organ with crucial functions in metabolism and immune defense, as well as blood homeostasis and detoxification, and it is clearly in bidirectional communication with the...
7.
Flanagan E, Spann R, Berry S, Berthoud H, Broyles S, Foster G, et al.
Obesity (Silver Spring) . 2023 Oct; 31(12):2895-2908. PMID: 37845825
Obesity is a chronic disease that affects more than 650 million adults worldwide. Obesity not only is a significant health concern on its own, but predisposes to cardiometabolic comorbidities, including...
8.
Munzberg H, Berthoud H, Neuhuber W
Mol Metab . 2023 Oct; 78:101817. PMID: 37806487
Interoception plays an important role in homeostatic regulation of energy intake and metabolism. Major interoceptive pathways include gut-to-brain and adipose tissue-to brain signaling via vagal sensory nerves and hormones, such...
9.
Axelrod C, Langohr I, Dantas W, Heintz E, Vandanmagsar B, Yang S, et al.
Obesity (Silver Spring) . 2023 Sep; 31(12):2960-2971. PMID: 37731222
Objective: Obesity is a driver of non-alcoholic fatty liver disease (NAFLD), and interventions that decrease body weight, such as bariatric surgery and/or calorie restriction (CR), may serve as effective therapies....
10.
Berthoud H
Am J Clin Nutr . 2023 Sep; 118(3):496-497. PMID: 37661103
No abstract available.