Christopher A McCulloch
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Explore the profile of Christopher A McCulloch including associated specialties, affiliations and a list of published articles.
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135
Citations
3398
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Recent Articles
11.
Ji C, Wang Y, Wang Q, Wang A, Ali A, McCulloch C
FASEB J
. 2023 May;
37(6):e22946.
PMID: 37219464
Transient Receptor Potential Vanilloid-type 4 (TRPV4) is a mechanosensitive, Ca -permeable plasma membrane channel that associates with focal adhesions, influences collagen remodeling, and is associated with fibrotic processes through undefined...
12.
Athanasiadou D, Meshry N, Monteiro N, Ervolino-Silva A, Chan R, McCulloch C, et al.
Proc Natl Acad Sci U S A
. 2023 Apr;
120(17):e2220565120.
PMID: 37071684
DNA-based biomaterials have been proposed for tissue engineering approaches due to their predictable assembly into complex morphologies and ease of functionalization. For bone tissue regeneration, the ability to bind Ca...
13.
Wade E, Goodin E, Wang Y, Morgan T, Callon K, Watson M, et al.
Bone Rep
. 2023 Mar;
18:101668.
PMID: 36909664
Mutations in , which encodes the cytoskeletal protein FLNA, cause a spectrum of sclerosing skeletal dysplasias. Although many of these genetic variants are recurrent and cluster within the gene, the...
14.
Huang B, Stewart C, McCulloch C, Santerre J, Cvitkovitch D, Finer Y
Dent J (Basel)
. 2022 Dec;
10(12).
PMID: 36547039
Here, we explored the role of S. mutans’s whole cell and discrete fractions in the degradation of type I collagen and dentinal collagen. Type I collagen gels and human demineralized...
15.
Quan B, Sadeghi R, Ikeda Y, Ganss B, Hamilton D, McCulloch C, et al.
Oral Dis
. 2022 Dec;
29(7):2845-2853.
PMID: 36458549
Objectives: Current methods for periodontal regeneration do not promote collagen fiber insertions into new bone and cementum. We used a pig wound model to screen different functionalized collagen membranes in...
16.
Ostrowska-Podhorodecka Z, Ding I, Norouzi M, McCulloch C
Front Cell Dev Biol
. 2022 Apr;
10:869069.
PMID: 35359446
Vimentin expression contributes to cellular mechanoprotection and is a widely recognized marker of fibroblasts and of epithelial-mesenchymal transition. But it is not understood how vimentin affects signaling that controls cell...
17.
Wang A, Coelho N, Arora P, Wang Y, Eymael D, Ji C, et al.
J Cell Physiol
. 2022 Feb;
237(5):2451-2468.
PMID: 35150133
Tissue fibrosis manifests as excessive deposition of compacted, highly aligned collagen fibrils, which interfere with organ structure and function. Cells in collagen-rich lesions often exhibit marked overexpression of discoidin domain...
18.
Mezawa M, Tsuruya Y, Yamaguchi A, Yamazaki-Takai M, Kono T, Okada H, et al.
Cell Adh Migr
. 2022 Feb;
16(1):13-24.
PMID: 35137648
Laminin 5, type 4 collagen, and α6β4 integrin contribute to the formation of hemidesmosomes in the epithelia of periodontal tissues, which is critical for the development and maintenance of the...
19.
Janmey P, Hinz B, McCulloch C
Physiology (Bethesda)
. 2021 Oct;
36(6):382-391.
PMID: 34704856
Cells spread on surfaces and within three-dimensional (3-D) matrixes as they grow, divide, and move. Both chemical and physical signals orchestrate spreading during normal development, wound healing, and pathological states...
20.
Jana S, Aujla P, Hu M, Kilic T, Zhabyeyev P, McCulloch C, et al.
FASEB J
. 2021 Sep;
35(10):e21932.
PMID: 34549830
Myocardial fibrosis is a characteristic of various cardiomyopathies, and myocardial fibroblasts play a central role in this process. Gelsolin (GSN) is an actin severing and capping protein that regulates actin...