Andras Kapus
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Explore the profile of Andras Kapus including associated specialties, affiliations and a list of published articles.
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Articles
122
Citations
4378
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Recent Articles
1.
Mukkala A, David B, Ailenberg M, Liang J, Vaswani C, Karakas D, et al.
Ann Surg
. 2025 Feb;
PMID: 39912224
Objective: To investigate the hepatoprotective effects of mitochondrial transplantation in a murine liver ischemia/reperfusion (I/R) model. Summary Background Data: Sequential liver ischemia followed by reperfusion (I/R) is a pathophysiological process...
2.
Mukkala A, Maksimoska V, Noble E, Ailenberg M, Petrut R, Goldfarb R, et al.
Shock
. 2024 Dec;
63(3):499-502.
PMID: 39617401
SR3677, a highly selective rho-associated protein kinase 2 inhibitor, administered prior to liver ischemia/reperfusion injury, induced hepatoprotection in both wild-type and Parkin2-/- mice. Experiments in hepatocytes identified BNIP3L/NIX, as a...
3.
Rzepka M, Raschzok S, Lee X, Yazaki K, Dauz J, Sun M, et al.
Am J Respir Cell Mol Biol
. 2024 Aug;
72(2):158-168.
PMID: 39163574
Right ventricular (RV) fibrosis is associated with RV dysfunction in a variety of RV pressure-loading conditions in which RV mechanical stress is increased, but the underlying mechanisms driving RV fibrosis...
4.
Venugopal S, Dan Q, Sri Theivakadadcham V, Wu B, Kofler M, Layne M, et al.
Am J Physiol Cell Physiol
. 2024 Jun;
327(2):C387-C402.
PMID: 38912734
RhoA and its effectors, the transcriptional coactivators myocardin-related transcription factor (MRTF) and serum response factor (SRF), control epithelial phenotype and are indispensable for profibrotic epithelial reprogramming during fibrogenesis. Context-dependent control...
5.
Myocardin-Related Transcription Factor Mediates Epithelial Fibrogenesis in Polycystic Kidney Disease
Lichner Z, Ding M, Khare T, Dan Q, Benitez R, Praszner M, et al.
Cells
. 2024 Jun;
13(11.
PMID: 38891116
Polycystic kidney disease (PKD) is characterized by extensive cyst formation and progressive fibrosis. However, the molecular mechanisms whereby the loss/loss-of-function of Polycystin 1 or 2 (PC1/2) provokes fibrosis are largely...
6.
Mukkala A, Jerkic M, Khan Z, Szaszi K, Kapus A, Rotstein O
Int J Mol Sci
. 2023 Nov;
24(21).
PMID: 37958771
Due to their beneficial effects in an array of diseases, Mesenchymal Stromal Cells (MSCs) have been the focus of intense preclinical research and clinical implementation for decades. MSCs have multilineage...
7.
Kofler M, Kapus A
Cancers (Basel)
. 2023 Oct;
15(20).
PMID: 37894323
Yes-associated Protein (YAP) and its paralog Transcriptional Coactivator with PDZ-binding Motif (TAZ) are major regulators of gene transcription/expression, primarily controlled by the Hippo pathway and the cytoskeleton. Integrating an array...
8.
Guo X, Khosraviani N, Raju S, Singh J, Farahani N, Abramian M, et al.
Front Immunol
. 2023 May;
14:1181016.
PMID: 37153544
Atypical chemokine receptor-1 (ACKR1), previously known as the Duffy antigen receptor for chemokines, is a widely conserved cell surface protein that is expressed on erythrocytes and the endothelium of post-capillary...
9.
Mukkala A, Petrut R, Goldfarb R, Beroncal E, Ho Leung C, Khan Z, et al.
Mitochondrion
. 2023 Mar;
70:20-30.
PMID: 36906251
Background And Aims: Hemorrhagic shock-resuscitation (HSR) following trauma contributes to organ dysfunction by causing ischemia-reperfusion injury (IRI). We previously showed that 'remote ischemic preconditioning' (RIPC) exerted multi-organ protection from IRI....
10.
Burger D, Abdelrasoul A, Alexander R, Ballermann B, Bridgewater D, Chan J, et al.
Can J Kidney Health Dis
. 2022 Dec;
9:20543581221144824.
PMID: 36545249
Purpose Of Conference: New discoveries arising from investigations into fundamental aspects of kidney development and function in health and disease are critical to advancing kidney care. Scientific meetings focused specifically...