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Christine J Boinett

Explore the profile of Christine J Boinett including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 902
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Recent Articles
1.
A Ghomi F, Jung J, Langridge G, Cain A, Boinett C, Abd El Ghany M, et al.
mBio . 2024 Aug; 15(10):e0179824. PMID: 39207104
The Enterobacteriaceae are a scientifically and medically important clade of bacteria, containing the model organism , as well as major human pathogens including and . Essential gene sets have been...
2.
Thorpe H, Pesonen M, Corbella M, Pesonen H, Gaiarsa S, Boinett C, et al.
Lancet Microbe . 2024 Aug; 5(10):100890. PMID: 39178869
Background: Nosocomial infections pose a considerable risk to patients who are susceptible, and this is particularly acute in intensive care units when hospital-associated bacteria are endemic. During the first wave...
3.
Waddington C, Carey M, Boinett C, Higginson E, Veeraraghavan B, Baker S
Genome Med . 2022 Feb; 14(1):15. PMID: 35172877
Antimicrobial resistance (AMR) is a major global public health threat, which has been largely driven by the excessive use of antimicrobials. Control measures are urgently needed to slow the trajectory...
4.
Maklin T, Kallonen T, David S, Boinett C, Pascoe B, Meric G, et al.
Wellcome Open Res . 2021 Nov; 5:14. PMID: 34746439
Determining the composition of bacterial communities beyond the level of a genus or species is challenging because of the considerable overlap between genomes representing close relatives. Here, we present the...
5.
Oppong E, Bao H, Tang W, Echavarria Mejia M, Glozah F, Asanga N, et al.
Am J Trop Med Hyg . 2021 Oct; 106(1):250-256. PMID: 34662869
Research mentoring programs are limited in many low- and middle-income countries (LMICs). The TDR Global initiated a global crowdsourcing open call soliciting proposals on how to improve research mentorship in...
6.
von Mentzer A, Blackwell G, Pickard D, Boinett C, Joffre E, Page A, et al.
Sci Rep . 2021 Apr; 11(1):9256. PMID: 33927221
Enterotoxigenic Escherichia coli (ETEC) is an enteric pathogen responsible for the majority of diarrheal cases worldwide. ETEC infections are estimated to cause 80,000 deaths annually, with the highest rates of...
7.
Da Silva K, Thi Nguyen T, Boinett C, Baker S, Simionatto S
Int J Med Microbiol . 2020 Oct; 310(7):151448. PMID: 33092694
The prevalence of polymyxin-resistant Enterobacteriaceae is increasing worldwide. Their emergence is worrisome and limits therapeutic options for severely ill patients. We aimed to investigate the molecular and epidemiological characteristics of...
8.
Elliott A, Huang J, Neve S, Zuegg J, Edwards I, Cain A, et al.
Nat Commun . 2020 Jun; 11(1):3184. PMID: 32576824
Peptide antibiotics are an abundant and synthetically tractable source of molecular diversity, but they are often cationic and can be cytotoxic, nephrotoxic and/or ototoxic, which has limited their clinical development....
9.
Da Silva K, Baker S, Croda J, Thi Nguyen T, Boinett C, Barbosa L, et al.
Int J Antimicrob Agents . 2020 Jan; 55(3):105882. PMID: 31923570
This study aimed to assess the clinical impact and potential risk factors associated with polymyxin-resistant Enterobacteriaceae strains isolated from patients hospitalized in adult and neonatal intensive care units. A case-control...
10.
Ellington M, Heinz E, Wailan A, Dorman M, de Goffau M, Cain A, et al.
Genome Biol . 2019 Sep; 20(1):184. PMID: 31477167
Background: Two of the most important pathogens contributing to the global rise in antimicrobial resistance (AMR) are Klebsiella pneumoniae and Enterobacter cloacae. Despite this, most of our knowledge about the...