Nicholas R Thomson
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Explore the profile of Nicholas R Thomson including associated specialties, affiliations and a list of published articles.
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278
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13956
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Recent Articles
1.
Mihaljevic L, Kim D, Eisenach H, Bandawane P, Borst A, Courbet A, et al.
bioRxiv
. 2025 Feb;
PMID: 39975033
The development of therapies and vaccines targeting integral membrane proteins has been complicated by their extensive hydrophobic surfaces, which can make production and structural characterization difficult. Here we describe a...
2.
Williams D, Hawkins A, Hernandez R, Mariano G, Mathers K, Buchanan G, et al.
Cell Host Microbe
. 2025 Jan;
33(2):252-266.e5.
PMID: 39884275
Opportunistic bacterial pathogens must compete with other bacteria and switch between host- and environment-adapted states. Type VI secretion systems (T6SSs) occur widely in gram-negative bacteria and can efficiently kill neighboring...
3.
Scott T, Baker K, Trotter C, Jenkins C, Mostowy S, Hawkey J, et al.
Nat Rev Microbiol
. 2024 Nov;
PMID: 39604656
Shigella sonnei is a major cause of diarrhoea globally and is increasing in prevalence relative to other Shigella because of multiple demographic and environmental influences. This single-serotype species has traditionally...
4.
Tsang K, Lam M, Wick R, Wyres K, Bachman M, Baker S, et al.
Microb Genom
. 2024 Oct;
10(10).
PMID: 39432416
Interpreting the phenotypes of alleles in genomes is complex. Whilst all strains are expected to carry a chromosomal copy conferring resistance to ampicillin, they may also carry mutations in chromosomal...
5.
Bote L, Taylor-Brown A, Maes M, Ingle D, Valcanis M, Howden B, et al.
Microb Genom
. 2024 Oct;
10(10).
PMID: 39412871
is a Gram-negative bacterium found in aquatic environments and is the aetiological agent of cholera, characterized by acute watery diarrhoea and severe dehydration. Cholera presents a significant global health burden...
6.
Wilson C, Musicha P, Beale M, Diness Y, Kanjerwa O, Salifu C, et al.
One Health
. 2024 Aug;
19:100848.
PMID: 39211934
was isolated from 23/79 (29.1%) pooled gecko stool samples from households in southern Malawi. Whole genome sequencing of 47 individual isolates within this collection revealed 27 serovars spanning two subspecies....
7.
A Ghomi F, Jung J, Langridge G, Cain A, Boinett C, Abd El Ghany M, et al.
mBio
. 2024 Aug;
15(10):e0179824.
PMID: 39207104
The Enterobacteriaceae are a scientifically and medically important clade of bacteria, containing the model organism , as well as major human pathogens including and . Essential gene sets have been...
8.
Thorpe H, Pesonen M, Corbella M, Pesonen H, Gaiarsa S, Boinett C, et al.
Lancet Microbe
. 2024 Aug;
5(10):100890.
PMID: 39178869
Background: Nosocomial infections pose a considerable risk to patients who are susceptible, and this is particularly acute in intensive care units when hospital-associated bacteria are endemic. During the first wave...
9.
Grillova L, Romeis E, Lieberman N, Tantalo L, Xu L, Molini B, et al.
Mol Microbiol
. 2024 Aug;
122(4):455-464.
PMID: 39115038
The recently discovered methodologies to cultivate and genetically manipulate Treponema pallidum subsp. pallidum (T. pallidum) have significantly helped syphilis research, allowing the in vitro evaluation of antibiotic efficacy, performance of...
10.
Seng R, Chomkatekaew C, Tandhavanant S, Saiprom N, Phunpang R, Thaipadungpanit J, et al.
Nat Commun
. 2024 Jul;
15(1):5699.
PMID: 38972886
Melioidosis is an often-fatal neglected tropical disease caused by an environmental bacterium Burkholderia pseudomallei. However, our understanding of the disease-causing bacterial lineages, their dissemination, and adaptive mechanisms remains limited. To...