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Christina Koutsari

Explore the profile of Christina Koutsari including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 790
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Recent Articles
1.
Chung J, Koutsari C, Blachnio-Zabielska A, Hames K, Jensen M
Am J Physiol Endocrinol Metab . 2017 Oct; 314(2):E105-E114. PMID: 28970356
We investigated the effects of meal ingestion on intramyofibrillar (IMF) and subsarcolemmal (SS) ceramide metabolism in volunteers ranging from lean to obese. Thirty-eight women and men underwent a steady-state meal...
2.
Chung J, Koutsari C, Blachnio-Zabielska A, Hames K, Jensen M
Diabetes . 2017 May; 66(8):2082-2091. PMID: 28483801
We investigated the relationship between insulin resistance markers and subsarcolemmal (SS) and intramyofibrillar (IMF) ceramide concentrations, as well as the contribution of plasma palmitate (6.5-h infusion of [U-C]palmitate) to intramyocellular...
3.
Ali A, Mundi M, Koutsari C, Bernlohr D, Jensen M
Diabetes . 2015 Apr; 64(8):2828-35. PMID: 25883112
Insulin stimulates the translocation fatty acid transport protein 1 (FATP1) to plasma membrane, and thus greater free fatty acid (FFA) uptake, in adipocyte cell models. Whether insulin stimulates greater FFA...
4.
Koutsari C, Mundi M, Ali A, Patterson B, Jensen M
Diabetes . 2013 Feb; 62(7):2386-95. PMID: 23434937
We measured the incorporation of systemic free fatty acids (FFA) into circulating very low-density lipoprotein triglycerides (VLDL-TGs) under postabsorptive, postprandial, and walking conditions in humans. Fifty-five men and 85 premenopausal...
5.
Koutsari C, Ali A, Mundi M, Jensen M
J Lipid Res . 2012 Oct; 54(1):254-64. PMID: 23093549
Accurate measures of plasma FA oxidation can improve our understanding of diseases characterized by impaired FA oxidation. We describe and compare the 24 h time-courses of FA oxidation using bolus...
6.
Blachnio-Zabielska A, Koutsari C, Tchkonia T, Jensen M
Obesity (Silver Spring) . 2012 Jun; 20(12):2341-7. PMID: 22677645
Ceramides (Cer) are implicated in obesity-associated skeletal muscle and perhaps adipocyte insulin resistance. We examined whether the sphingolipid content of human subcutaneous adipose tissue and plasma varies by obesity and...
7.
Blachnio-Zabielska A, Persson X, Koutsari C, Zabielski P, Jensen M
Rapid Commun Mass Spectrom . 2012 Apr; 26(9):1134-40. PMID: 22467464
Rationale: Sphingolipids are important components of cell membranes that serve as cell signaling molecules; ceramide plays a central role in sphingolipid metabolism. De novo ceramide biosynthesis depends on fatty acid...
8.
Koutsari C, Mundi M, Ali A, Jensen M
Diabetes . 2012 Jan; 61(2):329-38. PMID: 22228715
We measured subcutaneous adipose tissue free fatty acid (FFA) storage rates in postprandial and walking conditions to better understand the contributions of this pathway to body fat distribution. Palmitate tracers...
9.
Ali A, Koutsari C, Mundi M, Stegall M, Heimbach J, Taler S, et al.
Diabetes . 2011 Aug; 60(9):2300-7. PMID: 21810594
Objective: Because direct adipose tissue free fatty acid (FFA) storage may contribute to body fat distribution, we measured FFA (palmitate) storage rates and fatty acid (FA) storage enzymes/proteins in omental...
10.
Blachnio-Zabielska A, Koutsari C, Jensen M
Rapid Commun Mass Spectrom . 2011 Jul; 25(15):2223-30. PMID: 21735505
Long-chain acyl-coenzymes A (acyl-CoAs) (LCACoA) are the activated forms of long-chain fatty acids and serve as key lipid metabolites. Excess accumulation of intracellular LCACoA, diacylglycerols (DAGs) and ceramides may create...