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Christian Lanciault

Explore the profile of Christian Lanciault including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 276
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Recent Articles
1.
Huang G, Ternes L, Lanciault C, MacPherson-Hawthorne K, Chang Y, Sears R, et al.
J Pathol . 2024 Oct; 264(4):411-422. PMID: 39435649
The basement membrane (BM) is among the predominant microenvironmental factors of normal epithelia and of precancerous epithelial lesions. Evidence suggests that the BM functions not only as a barrier to...
2.
Chen E, Kardosh A, Nabavizadeh N, Foster B, Mayo S, Billingsley K, et al.
Cancer Med . 2023 May; 12(12):12986-12995. PMID: 37132281
Background: Neoadjuvant treatment with nab-paclitaxel and gemcitabine for potentially operable pancreatic adenocarcinoma has not been well studied in a prospective interventional trial and could down-stage tumors to achieve negative surgical...
3.
Dalwadi D, Torrens L, Abril-Fornaguera J, Pinyol R, Willoughby C, Posey J, et al.
Mol Ther . 2021 Feb; 29(2):680-690. PMID: 33554867
Adeno-associated virus (AAV) integrates into host genomes at low frequency, but when integration occurs in oncogenic hotspots it can cause hepatocellular carcinoma (HCC). Given the possibility of recombinant AAV (rAAV)...
4.
Ternes L, Huang G, Lanciault C, Thibault G, Riggers R, Gray J, et al.
Sci Rep . 2020 Dec; 10(1):20904. PMID: 33262400
Mechanistic disease progression studies using animal models require objective and quantifiable assessment of tissue pathology. Currently quantification relies heavily on staining methods which can be expensive, labor/time-intensive, inconsistent across laboratories...
5.
Burlingame E, McDonnell M, Schau G, Thibault G, Lanciault C, Morgan T, et al.
Sci Rep . 2020 Oct; 10(1):17507. PMID: 33060677
Spatially-resolved molecular profiling by immunostaining tissue sections is a key feature in cancer diagnosis, subtyping, and treatment, where it complements routine histopathological evaluation by clarifying tumor phenotypes. In this work,...
6.
Walker B, Zarour L, Wieghard N, Gallagher A, Swain J, Weinmann S, et al.
World J Surg . 2020 Jul; 44(10):3501-3509. PMID: 32647988
Background: Colorectal cancer (CRC) ranks second in cancer deaths worldwide and presents multiple management challenges, one of which is identifying high risk stage II disease that may benefit from adjuvant...
7.
Davis D, Tretiakova M, Kizzar C, Woltjer R, Krajbich V, Tykodi S, et al.
Ann Diagn Pathol . 2020 May; 47:151537. PMID: 32454441
Studies assessing tumor-infiltrating lymphocytes (TILs) in clear cell renal cell carcinoma (ccRCC) and clinical outcomes have mixed results. Given fundamental interaction of MHC class I with CD8+ T-cells, we hypothesized...
8.
Siddharthan R, Lanciault C, Tsikitis V
Ann Gastroenterol . 2019 May; 32(3):257-263. PMID: 31040622
Anal intraepithelial neoplasia (AIN) is a premalignant lesion for anal cancer. It is more commonly found in high-risk patients (e.g., human papilloma virus (HPV)/human immunodeficiency virus infections, post-organ transplantation patients,...
9.
Ruhl R, Rana S, Kelley K, Espinosa-Diez C, Hudson C, Lanciault C, et al.
BMC Cancer . 2018 May; 18(1):517. PMID: 29720118
Background: Colorectal cancer (CRC) is a leading cause of cancer-related death. The biologic response of CRC to standard of care adjuvant therapies such as chemotherapy and radiation are poorly understood....
10.
Farrell A, Joly M, Allen-Petersen B, Worth P, Lanciault C, Sauer D, et al.
Nat Commun . 2017 Nov; 8(1):1728. PMID: 29170413
Intratumoral phenotypic heterogeneity has been described in many tumor types, where it can contribute to drug resistance and disease recurrence. We analyzed ductal and neuroendocrine markers in pancreatic ductal adenocarcinoma,...