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Christa S Zerbe

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Articles 82
Citations 2495
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Recent Articles
11.
Bhattacharya S, Wong U, Khalid M, Blaney H, Menkart M, Oringher J, et al.
J Gastroenterol Hepatol . 2023 Sep; 38(12):2083-2089. PMID: 37743535
Background And Aim: Patients with chronic granulomatous disease (CGD) may develop inflammatory bowel disease (IBD). Characterization of small bowel disease in this cohort is scarce. Here, we sought to determine...
12.
Chandrasekaran P, Han Y, Zerbe C, Heller T, DeRavin S, Kreuzberg S, et al.
J Allergy Clin Immunol . 2023 Sep; 152(6):1619-1633.e11. PMID: 37659505
Background: Chronic granulomatous disease (CGD) is caused by defects in any 1 of the 6 subunits forming the nicotinamide adenine dinucleotide phosphate oxidase complex 2 (NOX2), leading to severely reduced...
13.
Strickland E, Pan D, Godfrey C, Kim J, Hopke A, Degrange M, et al.
bioRxiv . 2023 Jul; PMID: 37425711
Neutrophils exhibit self-amplified swarming to sites of injury and infection. How swarming is controlled to ensure the proper level of neutrophil recruitment is unknown. Using an model of infection, we...
14.
Beers B, Similuk M, Ghosh R, Seifert B, Jamal L, Kamen M, et al.
Front Immunol . 2023 May; 14:1172004. PMID: 37215141
Purpose: Though copy number variants (CNVs) have been suggested to play a significant role in inborn errors of immunity (IEI), the precise nature of this role remains largely unexplored. We...
15.
Sparks R, Rachmaninoff N, Hirsch D, Bansal N, Lau W, Martins A, et al.
Res Sq . 2023 Mar; PMID: 36993430
Monogenic diseases are often studied in isolation due to their rarity. Here we utilize multiomics to assess 22 monogenic immune-mediated conditions with age- and sex-matched healthy controls. Despite clearly detectable...
16.
Yang A, Sullivan B, Zerbe C, de Ravin S, Blakely A, Quezado M, et al.
J Allergy Clin Immunol Pract . 2023 Jan; 11(5):1401-1416. PMID: 36646382
Chronic granulomatous disease (CGD) is a rare inborn error of immunity, resulting from a defect in nicotinamide adenine dinucleotide phosphate oxidation and decreased production of phagocyte reactive oxygen species. The...
17.
Drummond R, Desai J, Hsu A, Oikonomou V, Vinh D, Acklin J, et al.
J Clin Invest . 2022 Nov; 132(22). PMID: 36377664
Subcutaneous phaeohyphomycosis typically affects immunocompetent individuals following traumatic inoculation. Severe or disseminated infection can occur in CARD9 deficiency or after transplantation, but the mechanisms protecting against phaeohyphomycosis remain unclear. We...
18.
Salvator H, Cheng A, Rosen L, Williamson P, Bennett J, Kashyap A, et al.
Respir Res . 2022 Oct; 23(1):280. PMID: 36221098
Background: Anti GM-CSF autoantibodies (aAb) have been related to acquired pulmonary alveolar proteinosis (PAP) and described in cases of severe infections such as cryptococcosis and nocardiosis in previously healthy subjects....
19.
Totten A, Uzel G, Khil P, Youn J, Treat J, Soutar C, et al.
Open Forum Infect Dis . 2022 Oct; 9(9):ofac472. PMID: 36196300
is a rare cause of invasive infection in immunodeficient hosts. Phosphatidylinositol 3-kinase, regulatory subunit 1 () mutations predispose patients to sinopulmonary infections, alongside bronchiectasis autoimmunity and lymphoproliferation. We report 2...
20.
Hsu A, Korzeniowska A, Aguilar C, Gu J, Karlins E, Oler A, et al.
JCI Insight . 2022 Sep; 7(22). PMID: 36166305
Disseminated coccidioidomycosis (DCM) is caused by Coccidioides, pathogenic fungi endemic to the southwestern United States and Mexico. Illness occurs in approximately 30% of those infected, less than 1% of whom...