Chris Mungall
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Explore the profile of Chris Mungall including associated specialties, affiliations and a list of published articles.
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28
Citations
3788
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Recent Articles
21.
Karp D, Marthandan N, Marsh S, Ahn C, Arnett F, DeLuca D, et al.
Hum Mol Genet
. 2009 Nov;
19(4):707-19.
PMID: 19933168
We describe a novel approach to genetic association analyses with proteins sub-divided into biologically relevant smaller sequence features (SFs), and their variant types (VTs). SFVT analyses are particularly informative for...
22.
Hancock J, Mallon A, Beck T, Gkoutos G, Mungall C, Schofield P
Mamm Genome
. 2009 Aug;
20(8):457-61.
PMID: 19649761
Now that the laboratory mouse genome is sequenced and the annotation of its gene content is improving, the next major challenge is the annotation of the phenotypic associations of mouse...
23.
Schober D, Smith B, Lewis S, Kusnierczyk W, Lomax J, Mungall C, et al.
BMC Bioinformatics
. 2009 Apr;
10:125.
PMID: 19397794
Background: A wide variety of ontologies relevant to the biological and medical domains are available through the OBO Foundry portal, and their number is growing rapidly. Integration of these ontologies,...
24.
Masci A, Arighi C, Diehl A, Lieberman A, Mungall C, Scheuermann R, et al.
BMC Bioinformatics
. 2009 Feb;
10:70.
PMID: 19243617
Background: Recent increases in the volume and diversity of life science data and information and an increasing emphasis on data sharing and interoperability have resulted in the creation of a...
25.
Yandell M, Moore B, Salas F, Mungall C, MacBride A, White C, et al.
PLoS Comput Biol
. 2008 Nov;
4(11):e1000218.
PMID: 18989397
The millions of mutations and polymorphisms that occur in human populations are potential predictors of disease, of our reactions to drugs, of predisposition to microbial infections, and of age-related conditions...
26.
Pfeiffer B, Jenett A, Hammonds A, Ngo T, Misra S, Murphy C, et al.
Proc Natl Acad Sci U S A
. 2008 Jul;
105(28):9715-20.
PMID: 18621688
We demonstrate the feasibility of generating thousands of transgenic Drosophila melanogaster lines in which the expression of an exogenous gene is reproducibly directed to distinct small subsets of cells in...
27.
Mabee P, Ashburner M, Cronk Q, Gkoutos G, Haendel M, Segerdell E, et al.
Trends Ecol Evol
. 2007 Apr;
22(7):345-50.
PMID: 17416439
Understanding the developmental and genetic underpinnings of particular evolutionary changes has been hindered by inadequate databases of evolutionary anatomy and by the lack of a computational approach to identify underlying...
28.
Smith B, Ceusters W, Klagges B, Kohler J, Kumar A, Lomax J, et al.
Genome Biol
. 2005 May;
6(5):R46.
PMID: 15892874
To enhance the treatment of relations in biomedical ontologies we advance a methodology for providing consistent and unambiguous formal definitions of the relational expressions used in such ontologies in a...
29.
Gardner M, Hall N, Fung E, White O, Berriman M, Hyman R, et al.
Nature
. 2002 Oct;
419(6906):498-511.
PMID: 12368864
The parasite Plasmodium falciparum is responsible for hundreds of millions of cases of malaria, and kills more than one million African children annually. Here we report an analysis of the...