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Chin Hong Tan

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Citations 516
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Recent Articles
1.
Kan C, Hilal S, Xu X, Venketasubramanian N, Chen C, Tan C
Acta Neuropsychiatr . 2025 Mar; :1-22. PMID: 40079790
Aim: Mild behavioral impairment (MBI) is a neurobehavioral prodrome to dementia with multiple phenotypic characteristics. To investigate the complex neurobiological substrate underlying MBI, we evaluated its association with a composite...
2.
Phang K, Tan C
Geroscience . 2025 Jan; PMID: 39873919
In Alzheimer's disease (AD), the accumulation of neuropathological markers such as amyloid-β plaques, neurofibrillary tangles, and cortical neurodegeneration occurs over many years before overt manifestation of cognitive impairment. There is...
3.
Kan C, Coenen M, Xu X, Hilal S, Barkhof F, Benke T, et al.
J Neurol Neurosurg Psychiatry . 2025 Jan; PMID: 39761997
Background: White matter hyperintensities (WMH) have been implicated in the pathogenesis of neuropsychiatric symptoms of dementia but the functional significance of WMH in specific white matter (WM) tracts is unclear....
4.
Tan J, Tan C, Kraus M
Affect Sci . 2024 Jul; 5(2):1-8. PMID: 39050038
Supplementary Information: The online version contains supplementary material available at 10.1007/s42761-023-00234-w.
5.
Tan C, Tan J
Int J Cardiol . 2024 Apr; 407:132037. PMID: 38604451
Background: White matter hyperintensities (WMHs) represent diffuse small vessel disease implicating the cardiac, systemic, and cerebral vasculatures. As the brain may be the end-organ of cumulative vascular disease, and higher...
6.
Tan J, Tan C, Kraus M
Affect Sci . 2024 Mar; 5(1):67. PMID: 38495782
[This corrects the article DOI: 10.1007/s42761-023-00234-w.].
7.
Mak E, Zhang L, Tan C, Reilhac A, Shim H, Wen M, et al.
Brain Commun . 2023 Jul; 5(4):fcad192. PMID: 37483530
How beta-amyloid accumulation influences brain atrophy in Alzheimer's disease remains contentious with conflicting findings. We aimed to elucidate the correlations of regional longitudinal atrophy with cross-sectional regional and global amyloid...
8.
Tan C, Tan J
Geroscience . 2023 Apr; 45(3):2027-2036. PMID: 37004594
There is increasing recognition that socioeconomic inequalities contribute to disparities in brain and cognitive health in older adults. However, whether neighborhood socioeconomic status (SES) buffers individuals with low individual SES...
9.
Tan C, Chew J, Zhang L, Gulyas B, Chen C
Neurobiol Aging . 2022 Apr; 115:12-19. PMID: 35453034
White matter hyperintensities (WMH) and β-amyloid (Aβ) accumulation have both been linked to neurodegeneration in Alzheimer's disease (AD). However, the independent effects of global WMH and regional Aβ on the...
10.
Kan C, Xu X, Schmetterer L, Venketasubramanian N, Chen C, Tan C
Neurobiol Aging . 2021 Nov; 109:239-246. PMID: 34814099
Comorbid neuropsychiatric symptoms are commonly found in individuals with dementia and is likely influenced by a combination of neurodegenerative and cerebrovascular pathophysiology. We evaluated the associations of a validated composite...