Chin Hong Tan
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Explore the profile of Chin Hong Tan including associated specialties, affiliations and a list of published articles.
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28
Citations
516
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Recent Articles
11.
Tanaka T, Ruifen J, Nai Y, Tan C, Lim C, Zhang Y, et al.
Eur J Neurol
. 2020 Dec;
28(5):1479-1489.
PMID: 33370497
Background And Purpose: Various blood biomarkers reflecting brain amyloid-β (Aβ) load have recently been proposed with promising results. However, to date, no comparative study amongst blood biomarkers has been reported....
12.
Fan C, Banks S, Thompson W, Chen C, McEvoy L, Tan C, et al.
Brain
. 2020 Jun;
143(7):2272-2280.
PMID: 32591829
Sex differences in the manifestations of Alzheimer's disease are under intense investigation. Despite the emerging importance of polygenic predictions for Alzheimer's disease, sex-dependent polygenic effects have not been demonstrated. Here,...
13.
Chiarelli A, Low K, Maclin E, Fletcher M, Kong T, Zimmerman B, et al.
Photonics
. 2020 May;
6(3).
PMID: 32377515
Aging is accompanied by widespread changes in brain tissue. Here, we hypothesized that head tissue opacity to near-infrared light provides information about the health status of the brain's cortical mantle....
14.
Kong T, Gratton C, Low K, Tan C, Chiarelli A, Fletcher M, et al.
Netw Neurosci
. 2020 Feb;
4(1):89-114.
PMID: 32043045
Age-related declines in cognition are associated with widespread structural and functional brain changes, including changes in resting-state functional connectivity and gray and white matter status. Recently we have shown that...
15.
Tan C, Hilal S, Xu X, Vrooman H, Cheng C, Wong T, et al.
J Alzheimers Dis
. 2020 Jan;
73(4):1501-1509.
PMID: 31958085
There is a need to elucidate the combined influence of neurodegeneration and cerebrovascular disease (CeVD) on cognitive impairment, especially in diverse populations. Here, we evaluated 840 multiethnic individuals (mean age ...
16.
Tan C, Low K, Chiarelli A, Fletcher M, Navarra R, Burzynska A, et al.
Neurobiol Aging
. 2019 Sep;
84:200-207.
PMID: 31500910
Decline in fluid abilities in normal aging is associated with increased white matter lesions, measured on T1-weighted images as white matter signal abnormalities (WMSAs). WMSAs are particularly evident in hypertensive...
17.
Tan C, Bonham L, Fan C, Mormino E, Sugrue L, Broce I, et al.
Brain
. 2019 Jan;
142(2):460-470.
PMID: 30689776
Mounting evidence indicates that the polygenic basis of late-onset Alzheimer's disease can be harnessed to identify individuals at greatest risk for cognitive decline. We have previously developed and validated a...
18.
Broce I, Tan C, Fan C, Jansen I, Savage J, Witoelar A, et al.
Acta Neuropathol
. 2018 Nov;
137(2):209-226.
PMID: 30413934
Cardiovascular (CV)- and lifestyle-associated risk factors (RFs) are increasingly recognized as important for Alzheimer's disease (AD) pathogenesis. Beyond the ε4 allele of apolipoprotein E (APOE), comparatively little is known about...
19.
Li Y, Barkovich M, Karch C, Nillo R, Fan C, Broce I, et al.
Sci Rep
. 2018 Sep;
8(1):13373.
PMID: 30190613
Tuberous sclerosis complex (TSC), a heritable neurodevelopmental disorder, is caused by mutations in the TSC1 or TSC2 genes. To date, there has been little work to elucidate regional TSC1 and...
20.
Barkovich M, Tan C, Nillo R, Li Y, Xu D, Glastonbury C, et al.
Radiology
. 2018 Sep;
289(2):499-508.
PMID: 30179114
Purpose To evaluate whether patients with neurofibromatosis type 1 (NF1)-a multisystem neurodevelopmental disorder with myriad imaging manifestations, including focal transient myelin vacuolization within the deep gray nuclei, brainstem, and cerebellum-exhibit...