Chika Yokota
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Explore the profile of Chika Yokota including associated specialties, affiliations and a list of published articles.
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30
Citations
1382
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Recent Articles
11.
Soldatov R, Kaucka M, Kastriti M, Petersen J, Chontorotzea T, Englmaier L, et al.
Science
. 2019 Jun;
364(6444).
PMID: 31171666
Neural crest cells are embryonic progenitors that generate numerous cell types in vertebrates. With single-cell analysis, we show that mouse trunk neural crest cells become biased toward neuronal lineages when...
12.
Tiklova K, Bjorklund A, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, et al.
Nat Commun
. 2019 Feb;
10(1):581.
PMID: 30718509
Midbrain dopamine (mDA) neurons constitute a heterogenous group of cells that have been intensely studied, not least because their degeneration causes major symptoms in Parkinson's disease. Understanding the diversity of...
13.
Asano M, Motoike S, Yokota C, Usuki N, Yamamoto H, Urabe T, et al.
J Pharmacol Sci
. 2018 Dec;
139(1):29-36.
PMID: 30522963
The serotonin transporter (SERT) is functionally regulated via membrane trafficking. Our previous studies have demonstrated that the SERT C-terminal deletion mutant (SERTΔCT) showed a robust decrease in its membrane trafficking...
14.
Strell C, Hilscher M, Laxman N, Svedlund J, Wu C, Yokota C, et al.
FEBS J
. 2018 Mar;
286(8):1468-1481.
PMID: 29542254
Single-cell transcriptomics provides us with completely new insights into the molecular diversity of different cell types and the different states they can adopt. The technique generates inventories of cells that...
15.
Hupe M, Li M, Kneitz S, Davydova D, Yokota C, Kele J, et al.
Sci Signal
. 2017 Jul;
10(487).
PMID: 28698213
The blood-brain barrier is a dynamic interface that separates the brain from the circulatory system, and it is formed by highly specialized endothelial cells. To explore the molecular mechanisms defining...
16.
Salasova A, Yokota C, Potesil D, Zdrahal Z, Bryja V, Arenas E
Mol Neurodegener
. 2017 Jul;
12(1):54.
PMID: 28697798
Background: Autosomal-dominant mutations in the Park8 gene encoding Leucine-rich repeat kinase 2 (LRRK2) have been identified to cause up to 40% of the genetic forms of Parkinson's disease. However, the...
17.
Yokota C, Astrand C, Takahashi S, Hagey D, Stenman J
Int J Dev Biol
. 2017 Jul;
61(6-7):415-425.
PMID: 28695961
In vertebrates, the neural crest and placodes originate in the neural border, which is located between the neural plate and epidermal ectoderm. The neural crest and placodes give rise to...
18.
Strakova K, Matricon P, Yokota C, Arthofer E, Bernatik O, Rodriguez D, et al.
Cell Signal
. 2017 Jul;
38:85-96.
PMID: 28668722
Frizzleds (FZDs) are unconventional G protein-coupled receptors, which activate diverse intracellular signaling pathways via the phosphoprotein Disheveled (DVL) and heterotrimeric G proteins. The interaction interplay of FZDs with DVL and...
19.
Zhang X, Abreu J, Yokota C, MacDonald B, Singh S, Coburn K, et al.
Cell
. 2012 Jun;
149(7):1565-77.
PMID: 22726442
Secreted Wnt morphogens are signaling molecules essential for embryogenesis, pathogenesis, and regeneration and require distinct modifications for secretion, gradient formation, and activity. Whether Wnt proteins can be posttranslationally inactivated during...
20.
MacDonald B, Yokota C, Tamai K, Zeng X, He X
J Biol Chem
. 2008 Mar;
283(23):16115-23.
PMID: 18362152
Low density lipoprotein receptor-related protein 6 (LRP6) and its homologue LRP5 serve as Wnt co-receptors that are essential for the Wnt/beta-catenin pathway. Wnt activation of LRP6 leads to recruitment of...