Chiara Romualdi
Overview
Explore the profile of Chiara Romualdi including associated specialties, affiliations and a list of published articles.
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146
Citations
3749
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Recent Articles
1.
Rigoni G, Calvo E, Glytsou C, Carro-Alvarellos M, Noguchi M, Semenzato M, et al.
Cell Metab
. 2025 Feb;
PMID: 39999845
Mitochondrial proteins assemble dynamically in high molecular weight complexes essential for their functions. We generated and validated two searchable compendia of these mitochondrial complexes. Following identification by mass spectrometry of...
2.
Potente S, Boscarino D, Paladin D, Marchini S, Beltrame L, Romualdi C
Brief Bioinform
. 2025 Jan;
26(1).
PMID: 39879385
Shallow whole-genome sequencing (sWGS) offers a cost-effective approach to detect copy number alterations (CNAs). However, there remains a gap for a standardized workflow specifically designed for sWGS analysis. To address...
3.
Boso D, Piga I, Trento C, Minuzzo S, Angi E, Iommarini L, et al.
J Exp Clin Cancer Res
. 2024 Dec;
43(1):325.
PMID: 39702370
Background: Mitochondrial DNA (mtDNA) pathogenic variants have been reported in several solid tumors including ovarian cancer (OC), the most lethal gynecologic malignancy, and raised interest as they potentially induce mitochondrial...
4.
Pirrotta S, Masatti L, Bortolato A, Corra A, Pedrini F, Aere M, et al.
NAR Genom Bioinform
. 2024 Oct;
6(4):lqae138.
PMID: 39363890
Understanding cancer mechanisms, defining subtypes, predicting prognosis and assessing therapy efficacy are crucial aspects of cancer research. Gene-expression signatures derived from bulk gene expression data have played a significant role...
5.
Prosdocimi E, Carpanese V, Todesca L, Varanita T, Bachmann M, Festa M, et al.
Sci Adv
. 2024 Sep;
10(36):eadn9361.
PMID: 39231216
Kv1.3 is a multifunctional potassium channel implicated in multiple pathologies, including cancer. However, how it is involved in disease progression is not fully clear. We interrogated the interactome of Kv1.3...
6.
Carpanese V, Festa M, Prosdocimi E, Bachmann M, Sadeghi S, Bertelli S, et al.
Cell Death Discov
. 2024 Aug;
10(1):387.
PMID: 39209805
No abstract available.
7.
Carpanese V, Festa M, Prosdocimi E, Bachmann M, Sadeghi S, Bertelli S, et al.
Cell Death Discov
. 2024 Jun;
10(1):299.
PMID: 38909013
Ion channels are critical in enabling ion movement into and within cells and are important targets for pharmacological interventions in different human diseases. In addition to their ion transport abilities,...
8.
Bonora M, Morganti C, van Gastel N, Ito K, Calura E, Zanolla I, et al.
Cell Stem Cell
. 2024 Mar;
31(3):359-377.e10.
PMID: 38458178
Mitochondrial fatty acid oxidation (FAO) is essential for hematopoietic stem cell (HSC) self-renewal; however, the mechanism by which mitochondrial metabolism controls HSC fate remains unknown. Here, we show that within...
9.
Paracchini L, Mannarino L, Romualdi C, Zadro R, Beltrame L, Fuso Nerini I, et al.
Sci Transl Med
. 2023 Dec;
15(725):eadi2556.
PMID: 38055801
Late diagnosis and the lack of screening methods for early detection define high-grade serous ovarian cancer (HGSOC) as the gynecological malignancy with the highest mortality rate. In the work presented...
10.
Muccioli S, Brillo V, Varanita T, Rossin F, Zaltron E, Velle A, et al.
Cell Death Dis
. 2023 Oct;
14(10):704.
PMID: 37898636
Skin cutaneous melanoma (SKCM) is the deadliest form of skin cancer due to its high heterogeneity that drives tumor aggressiveness. Melanoma plasticity consists of two distinct phenotypic states that co-exist...