Massimo Castagnola
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Explore the profile of Massimo Castagnola including associated specialties, affiliations and a list of published articles.
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200
Citations
1831
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Recent Articles
1.
Muntiu A, Moresi F, Vincenzoni F, Rossetti D, Iavarone F, Messana I, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684695
Glioblastoma multiforme (GBM) is an extremely aggressive brain tumor characterized by a high infiltration capability and recurrence rate. Early diagnosis is crucial to improve the prognosis and to personalize the...
2.
Fraschini M, Castagnola M, Barberini L, Sanfilippo R, Coghe F, Didaci L, et al.
Sensors (Basel)
. 2024 Aug;
24(16).
PMID: 39205077
Stroke is the second leading cause of death and a major cause of disability around the world, and the development of atherosclerotic plaques in the carotid arteries is generally considered...
3.
Contini C, Manconi B, Olianas A, Guadalupi G, Schirru A, Zorcolo L, et al.
Cells
. 2024 Aug;
13(16.
PMID: 39195201
Colorectal cancer (CRC) is a frequent, worldwide tumor described for its huge complexity, including inter-/intra-heterogeneity and tumor microenvironment (TME) variability. Intra-tumor heterogeneity and its connections with metabolic reprogramming and epithelial-mesenchymal...
4.
Faa G, Coghe F, Pretta A, Castagnola M, Van Eyken P, Saba L, et al.
Diagnostics (Basel)
. 2024 Aug;
14(15).
PMID: 39125481
With the advent of whole-slide imaging (WSI), a technology that can digitally scan whole slides in high resolution, pathology is undergoing a digital revolution. Detecting microsatellite instability (MSI) in colorectal...
5.
Faa G, Messana I, Coni P, Piras M, Pichiri G, Piludu M, et al.
Cells
. 2024 Jul;
13(13.
PMID: 38994967
This review summarizes the results of a series of studies performed by our group with the aim to define the expression levels of thymosin β and thymosin β over time,...
6.
Ziranu P, Pretta A, Aimola V, Cau F, Mariani S, DAgata A, et al.
Cancers (Basel)
. 2024 Apr;
16(8).
PMID: 38672650
Cluster of differentiation 44 (CD44) is a non-kinase cell surface glycoprotein. It is overexpressed in several cell types, including cancer stem cells (CSCs). Cells overexpressing CD44 exhibit several CSC traits,...
7.
Di Pietro L, Boroumand M, Lattanzi W, Manconi B, Salvati M, Cabras T, et al.
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834461
Saliva houses over 2000 proteins and peptides with poorly clarified functions, including proline-rich proteins, statherin, P-B peptides, histatins, cystatins, and amylases. Their genes are poorly conserved across related species, reflecting...
8.
Serrao S, Contini C, Guadalupi G, Olianas A, Lai G, Messana I, et al.
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834061
Mastocytosis, a rare blood disorder characterized by the proliferation of clonal abnormal mast cells, has a variegated clinical spectrum and diagnosis is often difficult and delayed. Recently we proposed the...
9.
Notari S, Gambardella G, Vincenzoni F, Desiderio C, Castagnola M, Bocedi A, et al.
Sci Rep
. 2023 Aug;
13(1):14113.
PMID: 37644064
Lactoferrin, a multifunctional iron-binding protein containing 16 disulfides, is actively studied for its antibacterial and anti-carcinogenic properties. However, scarce information is nowadays available about its oxidative folding starting from the...
10.
Messana I, Manconi B, Cabras T, Boroumand M, Sanna M, Iavarone F, et al.
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628956
In this review, we extensively describe the main post-translational modifications that give rise to the multiple proteoforms characterized to date in the human salivary proteome and their potential role. Most...