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Ilaria Zuliani

Explore the profile of Ilaria Zuliani including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 157
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Recent Articles
1.
Cimini F, Barchetta I, Zuliani I, Pagnotta S, Bertoccini L, Dule S, et al.
Life Sci . 2021 Aug; 284:119913. PMID: 34453944
Aim: Biliverdin reductase-A (BVR-A) other than its canonical role in the degradation pathway of heme as partner of heme oxygenase-1 (HO1), has recently drawn attention as a protein with pleiotropic...
2.
Zuliani I, Lanzillotta C, Tramutola A, Barone E, Perluigi M, Rinaldo S, et al.
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33916835
The disturbance of protein O-GlcNAcylation is emerging as a possible link between altered brain metabolism and the progression of neurodegeneration. As observed in brains with Alzheimer's disease (AD), flaws of...
3.
Zuliani I, Lanzillotta C, Tramutola A, Francioso A, Pagnotta S, Barone E, et al.
Neurotherapeutics . 2020 Dec; 18(1):340-363. PMID: 33258073
Protein O-GlcNAcylation is a nutrient-related post-translational modification that, since its discovery some 30 years ago, has been associated with the development of neurodegenerative diseases. As reported in Alzheimer's disease (AD),...
4.
Lanzillotta C, Zuliani I, Tramutola A, Barone E, Blarzino C, Folgiero V, et al.
Prog Neurobiol . 2020 Aug; 196:101892. PMID: 32795489
A major challenge in neurobiology is the identification of the mechanisms by which protein misfolding leads to cellular toxicity. Many neurodegenerative disorders, in which aberrant protein conformers aggregate into pathological...
5.
Lanzillotta C, Zuliani I, Vasavda C, Snyder S, Paul B, Perluigi M, et al.
Antioxidants (Basel) . 2020 Jul; 9(8). PMID: 32727065
Biliverdin reductase-A (BVR-A) impairment is associated with increased accumulation of oxidatively-damaged proteins along with the impairment of autophagy in the brain during neurodegenerative disorders. Reduced autophagy inhibits the clearance of...
6.
Zuliani I, Urbinati C, Valenti D, Quattrini M, Medici V, Cosentino L, et al.
J Clin Med . 2020 Jun; 9(6). PMID: 32492904
Metformin is the first-line therapy for diabetes, even in children, and a promising attractive candidate for drug repurposing. Mitochondria are emerging as crucial targets of metformin action both in the...
7.
Di Domenico F, Zuliani I, Tramutola A
Expert Rev Proteomics . 2019 Nov; 16(11-12):951-964. PMID: 31709850
: Autophagy is one of the most conserved clearance systems through which eukaryotes manage to handle dysfunctional and excess organelles and macromolecules. This catabolic process has not only a role...
8.
Di Domenico F, Tramutola A, Barone E, Lanzillotta C, Defever O, Arena A, et al.
Redox Biol . 2019 Mar; 23:101162. PMID: 30876754
Increasing evidences support the notion that the impairment of intracellular degradative machinery is responsible for the accumulation of oxidized/misfolded proteins that ultimately results in the deposition of protein aggregates. These...
9.
Tramutola A, Lanzillotta C, Barone E, Arena A, Zuliani I, Mosca L, et al.
Transl Neurodegener . 2018 Nov; 7:28. PMID: 30410750
Background: Down syndrome (DS) individuals, by the age of 40s, are at increased risk to develop Alzheimer-like dementia, with deposition in brain of senile plaques and neurofibrillary tangles. Our laboratory...