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Chi Nam Ignatius Pang

Explore the profile of Chi Nam Ignatius Pang including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 323
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Recent Articles
1.
Wu W, Pang C, Mediati D, Tree J
mSystems . 2024 Mar; 9(4):e0097123. PMID: 38534138
Importance: The emergence of multidrug-resistant (MRSA) is a major public health concern. Current treatment is dependent on the efficacy of last-line antibiotics like vancomycin. The most common cause of vancomycin...
2.
Wu W, Pang C, Tree J, Mediati D
Methods Enzymol . 2023 Nov; 692:299-324. PMID: 37925184
Regulatory small RNA (sRNA) have been extensively studied in model Gram-negative bacteria, but the functional characterisation of these post-transcriptional gene regulators in Gram-positives remains a major challenge. Our previous work...
3.
Meagher N, Gorringe K, Wakefield M, Bolithon A, Pang C, Chiu D, et al.
Clin Cancer Res . 2022 Oct; 28(24):5383-5395. PMID: 36222710
Purpose: Advanced-stage mucinous ovarian carcinoma (MOC) has poor chemotherapy response and prognosis and lacks biomarkers to aid stage I adjuvant treatment. Differentiating primary MOC from gastrointestinal (GI) metastases to the...
4.
Mediati D, Wong J, Gao W, McKellar S, Pang C, Wu S, et al.
Nat Commun . 2022 Sep; 13(1):5683. PMID: 36167839
No abstract available.
5.
Mediati D, Wong J, Gao W, McKellar S, Pang C, Wu S, et al.
Nat Commun . 2022 Jun; 13(1):3558. PMID: 35732665
Treatment of methicillin-resistant Staphylococcus aureus infections is dependent on the efficacy of last-line antibiotics including vancomycin. Treatment failure is commonly linked to isolates with intermediate vancomycin resistance (termed VISA). These...
6.
Ehteda A, Simon S, Franshaw L, Giorgi F, Liu J, Joshi S, et al.
Cell Rep . 2021 Apr; 35(2):108994. PMID: 33852836
Diffuse intrinsic pontine glioma (DIPG) is an aggressive and incurable childhood brain tumor for which new treatments are needed. CBL0137 is an anti-cancer compound developed from quinacrine that targets facilitates...
7.
Separovich R, Pang C, Wilkins M
Trends Biochem Sci . 2020 Sep; 45(12):1035-1048. PMID: 32888772
Histone methylation is central to the regulation of eukaryotic transcription. Here, we review how the histone methylation system itself is regulated. There is substantial evidence that mammalian histone methyltransferases and...
8.
Pang C, Ballouz S, Weissberger D, Thibaut L, Hamey J, Gillis J, et al.
Mol Cell Proteomics . 2020 Aug; 19(11):1876-1895. PMID: 32817346
Co-fractionation MS (CF-MS) is a technique with potential to characterize endogenous and unmanipulated protein complexes on an unprecedented scale. However this potential has been offset by a lack of guidelines...
9.
Bartolec T, Smith D, Pang C, Xu Y, Hamey J, Wilkins M
Anal Chem . 2019 Dec; 92(2):1874-1882. PMID: 31851481
has the most comprehensively characterized protein-protein interaction network, or interactome, of any eukaryote. This has predominantly been generated through multiple, systematic studies of protein-protein interactions by two-hybrid techniques and of...
10.
Lai Y, Pang C, Campbell L, Chen S, Wilkins M, Carter D
Front Microbiol . 2019 Oct; 10:2195. PMID: 31632362
Fungal infections are an increasing cause of morbidity and mortality. Current antifungal drugs are limited in spectrum, few new drugs are in development, and resistance is an increasing issue. Drug...