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Daniel G Mediati

Explore the profile of Daniel G Mediati including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 149
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Recent Articles
1.
Mediati D, Blair T, Costas A, Monahan L, Soderstrom B, Charles I, et al.
mSystems . 2024 Sep; 9(10):e0038724. PMID: 39287381
Importance: Urinary tract infections (UTIs) are one of the most frequent infections worldwide. Uropathogenic (UPEC), which accounts for ~80% of UTIs, must rapidly adapt to highly variable host environments, such...
2.
Mediati D, Dan W, Lalaouna D, Dinh H, Pokhrel A, Rowell K, et al.
Cell Rep . 2024 Apr; 43(4):114082. PMID: 38583155
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are alarmingly common, and treatment is confined to last-line antibiotics. Vancomycin is the treatment of choice for MRSA bacteremia, and treatment failure is...
3.
Wu W, Pang C, Mediati D, Tree J
mSystems . 2024 Mar; 9(4):e0097123. PMID: 38534138
Importance: The emergence of multidrug-resistant (MRSA) is a major public health concern. Current treatment is dependent on the efficacy of last-line antibiotics like vancomycin. The most common cause of vancomycin...
4.
Wu W, Pang C, Tree J, Mediati D
Methods Enzymol . 2023 Nov; 692:299-324. PMID: 37925184
Regulatory small RNA (sRNA) have been extensively studied in model Gram-negative bacteria, but the functional characterisation of these post-transcriptional gene regulators in Gram-positives remains a major challenge. Our previous work...
5.
Davies M, Keller N, Brouwer S, Jespersen M, Cork A, Hayes A, et al.
Nat Commun . 2023 Feb; 14(1):1051. PMID: 36828918
A new variant of Streptococcus pyogenes serotype M1 (designated 'M1') has been reported in the United Kingdom, linked with seasonal scarlet fever surges, marked increase in invasive infections, and exhibiting...
6.
Mediati D, Wong J, Gao W, McKellar S, Pang C, Wu S, et al.
Nat Commun . 2022 Sep; 13(1):5683. PMID: 36167839
No abstract available.
7.
Mediati D, Wong J, Gao W, McKellar S, Pang C, Wu S, et al.
Nat Commun . 2022 Jun; 13(1):3558. PMID: 35732665
Treatment of methicillin-resistant Staphylococcus aureus infections is dependent on the efficacy of last-line antibiotics including vancomycin. Treatment failure is commonly linked to isolates with intermediate vancomycin resistance (termed VISA). These...
8.
McKellar S, Ivanova I, Arede P, Zapf R, Mercier N, Chu L, et al.
Nat Commun . 2022 Jun; 13(1):3560. PMID: 35732654
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen responsible for significant human morbidity and mortality. Post-transcriptional regulation by small RNAs (sRNAs) has emerged as an important mechanism for controlling virulence....
9.
Mediati D, Lalaouna D, Tree J
mBio . 2021 Aug; 12(4):e0104121. PMID: 34372700
Regulatory RNAs have emerged as ubiquitous gene regulators in all bacterial species studied to date. The combination of sequence-specific RNA interactions and malleable RNA structure has allowed regulatory RNA to...
10.
Mediati D, Wu S, Wu W, Tree J
Trends Genet . 2020 Sep; 37(1):35-45. PMID: 32951948
The golden age of antibiotics has passed, and the threat of untreatable antimicrobial resistant infections is now a reality for many individuals. Understanding how bacteria resist antimicrobial treatment and regulate...