Cheryl F Lichti
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Explore the profile of Cheryl F Lichti including associated specialties, affiliations and a list of published articles.
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2500
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Recent Articles
11.
Vomund A, Lichti C, Peterson O, Arbelaez A, Wan X, Unanue E
J Exp Med
. 2021 Apr;
218(6).
PMID: 33822842
Assessing the self-peptides presented by susceptible major histocompatibility complex (MHC) molecules is crucial for evaluating the pathogenesis and therapeutics of tissue-specific autoimmune diseases. However, direct examination of such MHC-bound peptides...
12.
Identification of spliced peptides in pancreatic islets uncovers errors leading to false assignments
Lichti C
Proteomics
. 2021 Feb;
21(7-8):e2000176.
PMID: 33548107
Proteasomal spliced peptides (PSPs) have been identified in the class I major histocompatibility complex (MHC) peptidomes of several tumors and have emerged as novel neoantigens that can stimulate highly specific...
13.
Acharya K, Nettles S, Lichti C, Warre-Cornish K, Polit L, Srivastava D, et al.
J Neuroendocrinol
. 2020 Oct;
32(10):e12904.
PMID: 33000549
Neural progestin receptors (PR) function in reproduction, neural development, neuroprotection, learning, memory and the anxiety response. In the absence of progestins, PR can be activated by dopamine (DA) in the...
14.
Wan X, Vomund A, Peterson O, Chervonsky A, Lichti C, Unanue E
Nat Immunol
. 2020 Apr;
21(5):589.
PMID: 32238948
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
15.
Wan X, Vomund A, Peterson O, Chervonsky A, Lichti C, Unanue E
Nat Immunol
. 2020 Mar;
21(4):455-463.
PMID: 32152506
The nature of autoantigens that trigger autoimmune diseases has been much discussed, but direct biochemical identification is lacking for most. Addressing this question demands unbiased examination of the self-peptides displayed...
16.
Alspach E, Lussier D, Miceli A, Kizhvatov I, DuPage M, Luoma A, et al.
Nature
. 2019 Oct;
574(7780):696-701.
PMID: 31645760
The ability of the immune system to eliminate and shape the immunogenicity of tumours defines the process of cancer immunoediting. Immunotherapies such as those that target immune checkpoint molecules can...
17.
Wan X, Zinselmeyer B, Zakharov P, Vomund A, Taniguchi R, Santambrogio L, et al.
Nature
. 2018 Jul;
560(7716):107-111.
PMID: 30022165
Tissue-specific autoimmunity occurs when selected antigens presented by susceptible alleles of the major histocompatibility complex are recognized by T cells. However, the reason why certain specific self-antigens dominate the response...
18.
Scala F, Nenov M, Crofton E, Singh A, Folorunso O, Zhang Y, et al.
Cell Rep
. 2018 Apr;
23(2):555-567.
PMID: 29642012
Resilience and vulnerability to neuropsychiatric disorders are linked to molecular changes underlying excitability that are still poorly understood. Here, we identify glycogen-synthase kinase 3β (GSK3β) and voltage-gated Na channel Nav1.6...
19.
Mostovenko E, Vegvari A, Rezeli M, Lichti C, Fenyo D, Wang Q, et al.
ACS Chem Neurosci
. 2017 Dec;
9(1):73-79.
PMID: 29254333
Glioblastoma (GBM), the most malignant of primary brain tumors, is a devastating and deadly disease, with a median survival of 14 months from diagnosis, despite standard regimens of radical brain...
20.
Acharya K, Nettles S, Sellers K, Im D, Harling M, Pattanayak C, et al.
eNeuro
. 2017 Sep;
4(5).
PMID: 28955722
Progestins bind to the progestin receptor (PR) isoforms, PR-A and PR-B, in brain to influence development, female reproduction, anxiety, and stress. Hormone-activated PRs associate with multiple proteins to form functional...