Chengxuan Chen
Overview
Explore the profile of Chengxuan Chen including associated specialties, affiliations and a list of published articles.
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17
Citations
487
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Recent Articles
1.
Chen C, Ge F, Du H, Sun Y, Sui Y, Tang S, et al.
Mol Plant
. 2025 Mar;
PMID: 40055894
Sorghum, the fifth most important food crop globally, serves not only as a source of silage forage, fiber, syrup, and biofuel, but also is widely recognized as an ideal model...
2.
Chen C, Zhang Z, Liu Y, Hong W, Karahan H, Wang J, et al.
Sci Adv
. 2025 Jan;
11(1):eadn1927.
PMID: 39752483
Alzheimer's disease (AD) is the leading dementia among the elderly with complex origins. Despite extensive investigation into the AD-associated protein-coding genes, the involvement of noncoding RNAs (ncRNAs) and posttranscriptional modification...
3.
Luo M, Yang J, Schaffer A, Chen C, Liu Y, Chen Y, et al.
Cancer Discov
. 2024 Nov;
15(3):511-529.
PMID: 39601595
Our study charts a global landscape of ancestry-associated differences in therapeutic efficacy, highlighting the importance of considering ancestry in anticancer therapies.
4.
Wang R, Chen C, Liu Y, Luo M, Yang J, Chen Y, et al.
Cancer Lett
. 2024 Oct;
605:217304.
PMID: 39426663
Small nucleolar RNAs (snoRNAs) are a class of non-coding RNAs primarily known for their role in the chemical modification of other RNAs. Recent studies suggested that snoRNAs may play a...
5.
Chen C, Liu Y, Luo M, Yang J, Chen Y, Wang R, et al.
Nucleic Acids Res
. 2023 Oct;
52(D1):D1400-D1406.
PMID: 37870463
Expression quantitative trait locus (eQTL) analysis is a powerful tool used to investigate genetic variations in complex diseases, including cancer. We previously developed a comprehensive database, PancanQTL, to characterize cancer...
6.
Liu Y, Yang J, Wang T, Luo M, Chen Y, Chen C, et al.
Nat Commun
. 2023 Oct;
14(1):6509.
PMID: 37845222
Proteolysis-targeting chimera (PROTAC) and other targeted protein degradation (TPD) molecules that induce degradation by the ubiquitin-proteasome system (UPS) offer new opportunities to engage targets that remain challenging to be inhibited...
7.
Chen C, Liu Y, Li Q, Zhang Z, Luo M, Liu Y, et al.
Cancer Res
. 2023 Aug;
83(22):3673-3680.
PMID: 37548539
Significance: Comprehensive characterization of the relationship between protein expression and the genetic, pharmacogenomic, and immune landscape of tumors across cancer types provides a foundation for investigating the role of protein...
8.
Chen C, Han L
Trends Genet
. 2023 Jun;
39(8):600-601.
PMID: 37295977
Multi-omic analysis is an effective approach for dissecting the mechanisms of diseases; however, collecting multi-omic data in large populations is time-consuming and costly. Recently, Xu et al. developed genetic scores...
9.
Zhang H, Yu F, Xie P, Sun S, Qiao X, Tang S, et al.
Science
. 2023 Mar;
379(6638):eade8416.
PMID: 36952416
The use of alkaline salt lands for crop production is hindered by a scarcity of knowledge and breeding efforts for plant alkaline tolerance. Through genome association analysis of sorghum, a...
10.
Xie P, Tang S, Chen C, Zhang H, Yu F, Li C, et al.
Nat Commun
. 2022 Feb;
13(1):1068.
PMID: 35217660
One of the most critical steps in cereal threshing is the ease with which seeds are detached from sticky glumes. Naked grains with low glume coverage have dramatically increased threshing...