Charu Shukla
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Explore the profile of Charu Shukla including associated specialties, affiliations and a list of published articles.
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8
Citations
222
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Recent Articles
1.
Hallows W, Skvorak K, Agard N, Kruse N, Zhang X, Zhu Y, et al.
Sci Rep
. 2023 Mar;
13(1):4748.
PMID: 36959353
Fabry disease is caused by a deficiency of α-galactosidase A (GLA) leading to the lysosomal accumulation of globotriaosylceramide (Gb3) and other glycosphingolipids. Fabry patients experience significant damage to the heart,...
2.
McKenna J, Thankachan S, Uygun D, Shukla C, McNally J, Schiffino F, et al.
Curr Biol
. 2020 May;
30(12):2379-2385.e4.
PMID: 32413301
The ability to rapidly arouse from sleep is important for survival. However, increased arousals in patients with sleep apnea and other disorders prevent restful sleep and contribute to cognitive, metabolic,...
3.
Thankachan S, Katsuki F, McKenna J, Yang C, Shukla C, Deisseroth K, et al.
Sci Rep
. 2019 Mar;
9(1):3607.
PMID: 30837664
The thalamic reticular nucleus (TRN) is implicated in schizophrenia pathology. However, it remains unclear whether alterations of TRN activity can account for abnormal electroencephalographic activity observed in patients, namely reduced...
4.
Zant J, Kim T, Prokai L, Szarka S, McNally J, McKenna J, et al.
J Neurosci
. 2016 Feb;
36(6):2057-67.
PMID: 26865627
Significance Statement: Optogenetics is a revolutionary tool to assess the roles of particular groups of neurons in behavioral functions, such as control of sleep and wakefulness. However, the interpretation of...
5.
Shukla C, Basheer R
Nat Sci Sleep
. 2016 Jan;
8:9-20.
PMID: 26793010
Sleep and energy balance are essential for health. The two processes act in concert to regulate central and peripheral homeostasis. During sleep, energy is conserved due to suspended activity, movement,...
6.
Gavini C, Mukherjee S, Shukla C, Britton S, Koch L, Shi H, et al.
Am J Physiol Endocrinol Metab
. 2014 Jan;
306(6):E635-47.
PMID: 24398400
A high-calorie diet accompanied by low levels of physical activity (PA) accounts for the widespread prevalence of obesity today, and yet some people remain lean even in this obesogenic environment....
7.
Shukla C, Britton S, Koch L, Novak C
Neuroreport
. 2012 May;
23(10):596-600.
PMID: 22643233
The brain melanocortin (MC) system is one of numerous overlapping systems regulating energy balance; it consists of peptides including α-melanocyte-stimulating hormone that act through melanocortin receptors (MCRs). Mutations and polymorphisms...
8.
Wang D, Shukla C, Liu X, Schoeb T, Clarke L, Bedwell D, et al.
Mol Genet Metab
. 2009 Sep;
99(1):62-71.
PMID: 19751987
Here we report the characterization of a knock-in mouse model for the autosomal recessive disorder mucopolysaccharidosis type I-Hurler (MPS I-H), also known as Hurler syndrome. MPS I-H is the most...