Charles P Lerner
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Explore the profile of Charles P Lerner including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
202
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Recent Articles
1.
Aubrecht J, Goad M, Czopik A, Lerner C, Johnson K, Simpson E, et al.
Drug Chem Toxicol
. 2011 Jul;
34(4):433-9.
PMID: 21740348
Aminoglycoside antibiotics have been in use since 1944 with the discovery of streptomycin. The aim of this study was to derive a new, highly resistant multicopy neo(R) transgenic mouse strain,...
2.
Wang Y, Xiao R, Yang F, Karim B, Iacovelli A, Cai J, et al.
Development
. 2005 Jun;
132(15):3537-48.
PMID: 15975938
Apert syndrome is an autosomal dominant disorder characterized by malformations of the skull, limbs and viscera. Two-thirds of affected individuals have a S252W mutation in fibroblast growth factor receptor 2...
3.
Banks K, Johnson K, Lerner C, Mahaffey C, Bronson R, Simpson E
Genomics
. 2003 Aug;
82(3):254-60.
PMID: 12906850
It is hypothesized that autosomal retroposons compensate for the loss of their inactivated essential X-chromosome progenitors during spermatogenesis. Here we test this Retroposon Compensatory Mechanism (RCM) hypothesis using the Zfy...
4.
Wang X, Phelan S, Forsman-Semb K, Taylor E, Petros C, Brown A, et al.
J Biol Chem
. 2003 May;
278(27):25179-90.
PMID: 12732627
Reactive oxygen species, especially hydrogen peroxide, are important in cellular signal transduction. However, excessive amounts of these species damage tissues and cells by oxidizing virtually all important biomolecules. Peroxiredoxin 6...
5.
Simpson E, Johnson K, Shirley B, Fang G, Bayleran J, Lerner C
Genesis
. 2002 Jul;
33(2):62-6.
PMID: 12112873
A mouse targeted for a Y Chromosome gene has not been reported. Because the Y Chromosome is present in only one copy, and most of its genes are critical for...