Charles J Dimitroff
Overview
Explore the profile of Charles J Dimitroff including associated specialties, affiliations and a list of published articles.
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43
Citations
1193
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Recent Articles
1.
Shil R, Mohammed N, Dimitroff C
Front Immunol
. 2024 Oct;
15:1469794.
PMID: 39386209
Galectin-9 (Gal-9) is a tandem-repeat galectin with diverse roles in immune homeostasis, inflammation, malignancy, and autoimmune diseases. In cancer, Gal-9 displays variable expression patterns across different tumor types. Its interactions...
2.
Souchak J, Mohammed N, Lau L, Dimitroff C
Front Immunol
. 2024 Jun;
15:1395714.
PMID: 38840921
Vascular cell adhesion is a complex orchestration of events that commonly feature lectin-ligand interactions between circulating cells, such as immune, stem, and tumor cells, and endothelial cells (ECs) lining post-capillary...
3.
Mohammed N, Lau L, Souchak J, Qiu S, Ahluwalia M, Osman I, et al.
J Invest Dermatol
. 2024 Mar;
144(9):2039-2051.e9.
PMID: 38458429
Melanoma poses a poor prognosis with high mortality rates upon metastasis. Exploring the molecular mechanisms governing melanoma progression paves the way for developing novel approaches to control melanoma metastasis and...
4.
5.
Behnoush A, Khalaji A, Alemohammad S, Kalantari A, Cannavo A, Dimitroff C
Front Immunol
. 2023 Mar;
14:1127247.
PMID: 36923399
Background: Galectins are an eleven-member class of lectins in humans that function as immune response mediators and aberrancies in their expression are commonly associated with immunological diseases. Several studies have...
6.
Mohammed N, Antonopoulos A, Dell A, Haslam S, Dimitroff C
Adv Cancer Res
. 2023 Feb;
157:157-193.
PMID: 36725108
Melanoma is a highly aggressive skin cancer with poor outcomes associated with distant metastasis. Intrinsic properties of melanoma cells alongside the crosstalk between melanoma cells and surrounding microenvironment determine the...
7.
Lau L, Mohammed N, Dimitroff C
Int J Mol Sci
. 2022 Dec;
23(24).
PMID: 36555198
Galectins are a family of ß-galactoside-binding proteins that play a variety of roles in normal physiology. In cancer, their expression levels are typically elevated and often associated with poor prognosis....
8.
Chakraborty A, Perez M, Carroll J, Antonopoulos A, Dell A, Ortega L, et al.
J Invest Dermatol
. 2022 Sep;
143(3):456-469.e8.
PMID: 36174713
The prognosis for patients with metastatic melanoma (MM) involving distant organs is grim, and treatment resistance is potentiated by tumor-initiating cells (TICs) that thrive under hypoxia. MM cells, including TICs,...
9.
Schatton T, Itoh Y, Martins C, Rasbach E, Singh P, Silva M, et al.
Cancer Res
. 2022 Aug;
82(20):3774-3784.
PMID: 35980306
Significance: Tim-3 is a growth-suppressive receptor intrinsic to melanoma cells, the blockade of which promotes MAPK-dependent tumorigenesis and thus counteracts antitumor activity of T-cell-directed Tim-3 inhibition.
10.
Chakraborty A, Mohammed N, Bernasconi A, Dimitroff C
Methods Mol Biol
. 2022 Mar;
2442:565-580.
PMID: 35320546
The reported roles of the β-galactoside-binding lectin family, known as galectins, in disease development have been advancing at a remarkable pace. Galectins and their glycan counter-receptor ligands are now considered...