Charles C T Hindmarch
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Explore the profile of Charles C T Hindmarch including associated specialties, affiliations and a list of published articles.
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34
Citations
454
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Recent Articles
11.
Bentley R, Hindmarch C, Dunham-Snary K, Snetsinger B, Mewburn J, Thebaud A, et al.
Genomics
. 2021 Jul;
113(5):3128-3140.
PMID: 34245829
The ductus arteriosus (DA) connects the fetal pulmonary artery and aorta, diverting placentally oxygenated blood from the developing lungs to the systemic circulation. The DA constricts in response to increases...
12.
Guo Q, Bartish M, Goncalves C, Huang F, Smith-Voudouris J, Krisna S, et al.
Cancer Res
. 2021 May;
81(14):3876-3889.
PMID: 33975880
Breast cancer diagnosed within 10 years following childbirth is defined as postpartum breast cancer (PPBC) and is highly metastatic. Interactions between immune cells and other stromal cells within the involuting...
13.
Martin A, Mecawi A, Antunes V, Yao S, Antunes-Rodrigues J, Paton J, et al.
Front Physiol
. 2021 Apr;
11:599507.
PMID: 33815127
The chronically increased blood pressure characteristic of essential hypertension represents an insidious and cumulative risk for cardiovascular disease. Essential hypertension is a multifactorial condition, with no known specific aetiology but...
14.
Ushida T, Kotani T, Moriyama Y, Hindmarch C, Cotechini T, Imai K, et al.
Reproduction
. 2021 Mar;
161(5):513-522.
PMID: 33666569
Women with a history of preeclampsia have an increased risk of subsequent cardiovascular and metabolic disease. While aberrant inflammation during pregnancy is associated with the development of preeclampsia, whether maternal...
15.
Graham C, Pare J, Cotechini T, Hopman W, Hindmarch C, Ghaffari A, et al.
Can Urol Assoc J
. 2021 Jan;
15(8):E412-E417.
PMID: 33410746
Introduction: While studies suggest that innate immune memory acquired by circulating monocytes may mediate the benefit of bacillus Calmette-Guérin (BCG) in the treatment of patients with high-risk non-muscle-invasive bladder cancer...
16.
Tian L, Wu D, Dasgupta A, Chen K, Mewburn J, Potus F, et al.
Circ Res
. 2020 Mar;
126(12):1723-1745.
PMID: 32216531
Rationale: Right ventricular (RV) fibrosis in pulmonary arterial hypertension contributes to RV failure. While RV fibrosis reflects changes in the function of resident RV fibroblasts (RVfib), these cells are understudied....
17.
Dasgupta A, Wu D, Tian L, Xiong P, Dunham-Snary K, Chen K, et al.
Compr Physiol
. 2020 Mar;
10(2):713-765.
PMID: 32163206
In lung vascular cells, mitochondria serve a canonical metabolic role, governing energy homeostasis. In addition, mitochondria exist in dynamic networks, which serve noncanonical functions, including regulation of redox signaling, cell...
18.
McNeill M, Wray J, Sala-Newby G, Hindmarch C, Smith S, Ebrahimighaei R, et al.
Biochim Biophys Acta Mol Cell Res
. 2020 Mar;
1867(7):118691.
PMID: 32119877
Actin dynamics regulate cell behaviour in response to physiological signals. Here we demonstrate a novel role for nuclear actin in inhibiting cell proliferation and migration. We demonstrate that physiological signals...
19.
Dasgupta A, Chen K, Wu D, Hoskin V, Mewburn J, Lima P, et al.
FASEB J
. 2020 Feb;
34(4):5106-5127.
PMID: 32068312
Excessive proliferation and apoptosis-resistance are hallmarks of cancer. Increased dynamin-related protein 1 (Drp1)-mediated mitochondrial fission is one of the mediators of this phenotype. Mitochondrial fission that accompanies the nuclear division...
20.
Dutra S, Paterson A, Monteiro L, Greenwood M, Greenwood M, Amaral L, et al.
Neuroendocrinology
. 2020 Jan;
111(1-2):70-86.
PMID: 31955161
Background/aims: Furosemide is a loop diuretic widely used in clinical practice for the treatment of oedema and hypertension. The aim of this study was to determine physiological and molecular changes...