Julian F R Paton
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Explore the profile of Julian F R Paton including associated specialties, affiliations and a list of published articles.
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294
Citations
5788
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Recent Articles
1.
Neumann S, Rodrigues J, Simpson L, Lawton C, Burden D, Kobetic M, et al.
J Physiol
. 2025 Feb;
603(6):1417-1437.
PMID: 39960462
Adults with hypertension have higher prevalence of vertebral artery hypoplasia (VAH), which is associated with lower resting cerebral blood flow (CBF). We examined whether VAH impacts the ability to regulate...
2.
Wittenberg P, McBryde F, Korsak A, Rodrigues K, Paton J, Marina N, et al.
J Physiol
. 2025 Feb;
PMID: 39924875
Maintaining sufficient cerebral blood flow is critical for brain function. There is evidence that one of the mechanisms that ensure adequate blood flow to the brain involves the regulation of...
3.
Dhingra R, MacFarlane P, Thomas P, Paton J, Dutschmann M
bioRxiv
. 2024 Nov;
PMID: 39605441
Like other brain circuits, the brainstem respiratory network is continually modulated by neurotransmitters that activate slow metabotropic receptors. In many cases, activation of these receptors only subtly modulates the respiratory...
4.
Plunkett M, Paton J, Fisher J
Exp Physiol
. 2024 Oct;
110(1):42-57.
PMID: 39453284
The autonomic regulation of the pulmonary vasculature has been under-appreciated despite the presence of sympathetic and parasympathetic neural innervation and adrenergic and cholinergic receptors on pulmonary vessels. Recent clinical trials...
5.
Argent L, Bose A, Paton J
J R Soc N Z
. 2024 Oct;
53(3):332-361.
PMID: 39439480
The classic peripheral chemoreflex response is a critical homeostatic mechanism. In healthy individuals, appropriate chemoreflex responses are triggered by acute activation of the carotid body - the principal chemosensory organ...
6.
7.
Chen C, Kolbe J, Paton J, Fisher J
Exp Physiol
. 2024 Oct;
110(1):15-22.
PMID: 39395197
Exercise intolerance and exertional dyspnoea are hallmarks of fibrosing interstitial lung disease (FILD) and are associated with worse prognosis and quality of life. Activation of pulmonary vagal afferents influences the...
8.
Sayegh A, Plunkett M, Babbage T, Dawes M, Paton J, Fisher J
J Physiol
. 2024 Sep;
PMID: 39276118
We tested the hypothesis that in human hypertension, an increased tonicity/sensitivity of the peripheral chemoreflex causes a sympathetically mediated restraint of nutritive blood flow to the exercising muscles. Fourteen patients...
9.
Plunkett M, Sayegh A, McWilliams T, Sithamparanathan S, Paton J, Fisher J
Eur Respir J
. 2024 Jun;
64(1).
PMID: 38871376
No abstract available.
10.
de Souza J, de Souza D, da Silva C, Martins Sa R, Paton J, da Silva M, et al.
Neuroscience
. 2024 May;
551:153-165.
PMID: 38821242
The dorsal motor nucleus of the vagus (DMV) contains parasympathetic motoneurons that project to the heart and lungs. These motoneurons control ventricular excitability/contractility and airways secretions/blood flow, respectively. However, their...