Chandrasekharam N Nagineni
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Explore the profile of Chandrasekharam N Nagineni including associated specialties, affiliations and a list of published articles.
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948
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Recent Articles
1.
Nagineni C, Naz S, Choudhuri R, Chandramouli G, Krishna M, Brender J, et al.
Int J Mol Sci
. 2021 Jun;
22(9).
PMID: 34063570
Understanding the global metabolic changes during the senescence of tumor cells can have implications for developing effective anti-cancer treatment strategies. Ionizing radiation (IR) was used to induce senescence in a...
2.
Kutty R, Samuel W, Duncan T, Postnikova O, Jaworski C, Nagineni C, et al.
Cytokine
. 2017 Oct;
104:147-150.
PMID: 29054724
The inflammatory response may contribute to retinal pigment epithelial (RPE) dysfunction associated with the pathogenesis of age-related macular degeneration (AMD). We investigated whether the inflammatory response affects the expression of...
3.
Kutty R, Samuel W, Boyce K, Cherukuri A, Duncan T, Jaworski C, et al.
Mol Vis
. 2016 Oct;
22:1156-1168.
PMID: 27733811
Purpose: Proinflammatory cytokines interferon gamma (IFN-γ), tumor necrosis factor alpha (TNF-α), and interleukin-1 beta (IL-1β) secreted by infiltrating lymphocytes or macrophages may play a role in triggering RPE dysfunction associated...
4.
Nagineni C, Kommineni V, Ganjbaksh N, Nagineni K, Hooks J, Detrick B
Aging Dis
. 2015 Dec;
6(6):444-55.
PMID: 26618046
Chemokine reeptor-3 (CCR-3) was shown to be associated with choroidal neovascularization (CNV) in age-related macular degeneration (AMD). AMD is a vision threatening retinal disease that affects the aging population world-wide....
5.
Nagineni C, William A, Cherukuri A, Samuel W, Hooks J, Detrick B
Cytokine
. 2015 Nov;
78:16-9.
PMID: 26615568
Ocular surface inflammation is one of the primary mechanisms associated with dysfunctional tear syndrome (DTS), also known as dry eye disease. DTS, more prevalent in older populations, causes ocular discomfort...
6.
Kutty R, Samuel W, Abay R, Cherukuri A, Nagineni C, Duncan T, et al.
Cytokine
. 2015 Apr;
74(2):335-8.
PMID: 25890876
Dysfunction of the retinal pigment epithelium (RPE) resulting from chronic inflammation is implicated in the pathogenesis of age-related macular degeneration (AMD). RPE cells adjacent to drusen deposits in the AMD...
7.
Sonoda S, Nagineni C, Kitamura M, Spee C, Kannan R, Hinton D
Cytokine
. 2014 Apr;
68(2):137-40.
PMID: 24758915
Connective tissue growth factor (CTGF) is known to be involved in retinal fibrotic disorders. We used human retinal pigment epithelial cells (HRPE), which play critical roles in retinal fibrosis, to...
8.
Nagineni C, Raju R, Nagineni K, Kommineni V, Cherukuri A, Kutty R, et al.
Aging Dis
. 2014 Apr;
5(2):88-100.
PMID: 24729934
Age-related macular degeneration (AMD) is a sight threating retinal eye disease that affects millions of aging individuals world-wide. Choroid-retinal pigment epithelium (RPE)-neuroretina axis in the posterior compartment of the eye...
9.
Hall B, Wankhade U, Konkel J, Cherukuri K, Nagineni C, Flanders K, et al.
J Biol Chem
. 2013 Sep;
288(44):32074-92.
PMID: 24056369
Three homologues of TGF-β exist in mammals as follows: TGF-β1, TGF-β2, and TGF-β3. All three proteins share high homology in their amino acid sequence, yet each TGF-β isoform has unique...
10.
Ling D, Liu B, Jawad S, Thompson I, Nagineni C, Dailey J, et al.
Br J Ophthalmol
. 2013 Apr;
97(7):934-8.
PMID: 23624272
Purpose: AS101 is a non-toxic organotellurium-IV compound with demonstrated immunomodulating activity in vitro and in vivo. Inflammatory responses are attributed to the pathophysiology of numerous ocular diseases. In this study,...