Chandramohan Wakade
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Explore the profile of Chandramohan Wakade including associated specialties, affiliations and a list of published articles.
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885
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Recent Articles
1.
Wakade C, Chong R, Seamon M, Purohit S, Giri B, Morgan J
Biomedicines
. 2021 Dec;
9(12).
PMID: 34944695
A six-month double-blind, placebo-controlled randomized study was conducted to ascertain whether low-dose daily niacin supplementation would improve motor symptoms in Parkinson's disease (PD) patients. A total of 47 PD patients...
2.
Chong R, Wakade C, Seamon M, Giri B, Morgan J, Purohit S
Front Aging Neurosci
. 2021 Jul;
13:667032.
PMID: 34220485
We previously reported that individuals with Parkinson's disease (PD) present with lower vitamin B3 levels compared to controls. It may be related to carbidopa interaction, defective tryptophan metabolism, and stresses...
3.
Giri B, Seamon M, Banerjee A, Chauhan S, Purohit S, Morgan J, et al.
Metab Brain Dis
. 2021 Apr;
37(6):1687-1696.
PMID: 33881722
Parkinson's disease (PD) is one of the most common neurodegenerative diseases after Alzheimer's disease (AD), afflicting adults above the age of sixty irrespective of gender, race, ethnicity, and social status....
4.
Purohit S, Tran P, Tran L, Bin Satter K, He M, Zhi W, et al.
Front Immunol
. 2021 Apr;
12:654233.
PMID: 33868296
Chronic low-grade inflammation is involved in the pathogenesis of type-1 diabetes (T1D) and its complications. In this cross-section study design, we investigated association between serum levels of soluble cytokine receptors...
5.
Karunaratne T, Okereke C, Seamon M, Purohit S, Wakade C, Sharma A
Nutrients
. 2020 Dec;
13(1).
PMID: 33374784
Dysbiosis is implicated by many studies in the pathogenesis of Parkinson's disease (PD). Advances in sequencing technology and computing have resulted in confounding data regarding pathogenic bacterial profiles in conditions...
6.
Giri B, Belanger K, Seamon M, Bradley E, Purohit S, Chong R, et al.
Int J Mol Sci
. 2019 Sep;
20(18).
PMID: 31540057
In this study, we used macrophage RAW264.7 cells to elucidate the molecular mechanism underlying the anti-inflammatory actions of niacin. Anti-inflammatory actions of niacin and a possible role of its receptor...
7.
Chong R, Albor L, Wakade C, Morgan J
J Transl Med
. 2018 Jul;
16(1):192.
PMID: 29996887
Background: Fatigue is a common problem among individuals with Parkinson's disease (PD). It may occur before the overt symptoms of bradykinesia, rigidity and tremor. Little is understood about how to...
8.
Wakade C, Giri B, Malik A, Khodadadi H, Morgan J, Chong R, et al.
J Neuroimmunol
. 2018 May;
320:76-79.
PMID: 29759143
Neuroinflammation remains a central piece in Parkinson's disease (PD) pathophysiology. However, mechanisms by which PD links to the neuroinflammation remain elusive. Here, for the first time, we report that lower...
9.
Sharma A, Kurek J, Morgan J, Wakade C, Rao S
Curr Gastroenterol Rep
. 2018 Jan;
20(1):1.
PMID: 29350301
Purpose Of Review: Chronic constipation is a common, nonmotor, and prodromal symptom in Parkinson's disease (PD). Its underlying neuropathology may provide pathophysiological insight into PD. Here, we critically review what...
10.
Wakade C, Chong R, Bradley E, Morgan J
Clin Case Rep
. 2015 Aug;
3(7):635-7.
PMID: 26273459
A 65-year-old male, Parkinson's disease patient, was evaluated for GPR109A expression, niacin index, UPDRS scale, handwriting test, and quality of sleep with and without niacin treatment. The evaluation was repeated...