Celina Garcia-Garcia
Overview
Explore the profile of Celina Garcia-Garcia including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
768
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0
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Recent Articles
1.
Gris-Oliver A, Ibrahim Y, Rivas M, Garcia-Garcia C, Sanchez-Guixe M, Ruiz-Pace F, et al.
Br J Cancer
. 2021 Mar;
124(9):1581-1591.
PMID: 33723394
Background: Eribulin is a microtubule-targeting agent approved for the treatment of advanced or metastatic breast cancer (BC) previously treated with anthracycline- and taxane-based regimens. PIK3CA mutation is associated with worse...
2.
Katsageorgiou V, Sona D, Zanotto M, Lassi G, Garcia-Garcia C, Tucci V, et al.
PLoS Biol
. 2018 May;
16(5):e2003663.
PMID: 29813050
Sleep science is entering a new era, thanks to new data-driven analysis approaches that, combined with mouse gene-editing technologies, show a promise in functional genomics and translational research. However, the...
3.
Maggi S, Balzani E, Lassi G, Garcia-Garcia C, Plano A, Espinoza S, et al.
Sci Rep
. 2017 Dec;
7(1):17765.
PMID: 29259298
Circadian clock is known to adapt to environmental changes and can significantly influence cognitive and physiological functions. In this work, we report specific behavioral, cognitive, and sleep homeostatic defects in...
4.
Lassi G, Maggi S, Balzani E, Cosentini I, Garcia-Garcia C, Tucci V
Genetics
. 2016 Sep;
204(3):1129-1138.
PMID: 27672097
Abnormal feeding behavior is one of the main symptoms of Prader-Willi syndrome (PWS). By studying a PWS mouse mutant line, which carries a paternally inherited deletion of the small nucleolar...
5.
Lassi G, Priano L, Maggi S, Garcia-Garcia C, Balzani E, El-Assawy N, et al.
Sleep
. 2015 Oct;
39(3):637-44.
PMID: 26446116
Study Objectives: Sleep-wake disturbances are often reported in Prader-Willi syndrome (PWS), a rare neurodevelopmental syndrome that is associated with paternally-expressed genomic imprinting defects within the human chromosome region 15q11-13. One...
6.
Garcia-Garcia C, Rivas M, Ibrahim Y, Calvo M, Gris-Oliver A, Rodriguez O, et al.
Clin Cancer Res
. 2015 Aug;
21(24):5499-5510.
PMID: 26272063
Purpose: PI3K pathway activation occurs in concomitance with RAS/BRAF mutations in colorectal cancer, limiting the sensitivity to targeted therapies. Several clinical studies are being conducted to test the tolerability and...
7.
Tinarelli F, Garcia-Garcia C, Nicassio F, Tucci V
Philos Trans R Soc Lond B Biol Sci
. 2014 Jan;
369(1637):20120471.
PMID: 24446504
Sleep homoeostasis refers to a process in which the propensity to sleep increases as wakefulness progresses and decreases as sleep progresses. Sleep is tightly organized around the circadian clock and...
8.
Serra V, Eichhorn P, Garcia-Garcia C, Ibrahim Y, Prudkin L, Sanchez G, et al.
J Clin Invest
. 2013 May;
123(6):2551-63.
PMID: 23635776
The PI3K signaling pathway regulates diverse cellular processes, including proliferation, survival, and metabolism, and is aberrantly activated in human cancer. As such, numerous compounds targeting the PI3K pathway are currently...
9.
Ibrahim Y, Garcia-Garcia C, Serra V, He L, Torres-Lockhart K, Prat A, et al.
Cancer Discov
. 2012 Aug;
2(11):1036-47.
PMID: 22915752
Unlabelled: PARP inhibitors are active in tumors with defects in DNA homologous recombination (HR) due to BRCA1/2 mutations. The phosphoinositide 3-kinase (PI3K) signaling pathway preserves HR steady state. We hypothesized...
10.
Garcia-Garcia C, Ibrahim Y, Serra V, Calvo M, Guzman M, Grueso J, et al.
Clin Cancer Res
. 2012 Mar;
18(9):2603-12.
PMID: 22407832
Purpose: The PI3K/Akt/mTOR pathway is an attractive target in HER2-positive breast cancer that is refractory to anti-HER2 therapy. The hypothesis is that the suppression of this pathway results in sensitization...