Cedric Mongellaz
Overview
Explore the profile of Cedric Mongellaz including associated specialties, affiliations and a list of published articles.
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22
Citations
1007
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Recent Articles
1.
Mongellaz C, Vicente R, Noroski L, Noraz N, Courgnaud V, Chinen J, et al.
Front Immunol
. 2023 Jun;
14:1155883.
PMID: 37313400
Introduction: ZAP-70, a protein tyrosine kinase recruited to the T cell receptor (TCR), initiates a TCR signaling cascade upon antigen stimulation. Mutations in the gene cause a combined immunodeficiency characterized...
2.
Babayeva R, Mongellaz C, Karakus I, Cansever M, Bilgic Eltan S, Catak M, et al.
Pediatr Allergy Immunol
. 2022 Mar;
33(3):e13756.
PMID: 35338726
No abstract available.
3.
Matias M, Yong C, Foroushani A, Goldsmith C, Mongellaz C, Sezgin E, et al.
Cell Rep
. 2021 Nov;
37(5):109911.
PMID: 34731632
Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show that cell-permeable α-ketoglutarate (αKG) alters the DNA methylation profile of naive...
4.
Lamure S, Van Laethem F, de Verbizier D, Lozano C, Gehlkopf E, Tudesq J, et al.
Cancers (Basel)
. 2021 Sep;
13(17).
PMID: 34503088
CD19-directed CAR T-cells have been remarkably successful in treating patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) and transformed follicular lymphoma (t-FL). In this cohort study, we treated 60...
5.
Gonzalez-Menendez P, Romano M, Yan H, Deshmukh R, Papoin J, Oburoglu L, et al.
Cell Rep
. 2021 Feb;
34(5):108723.
PMID: 33535038
The metabolic changes controlling the stepwise differentiation of hematopoietic stem and progenitor cells (HSPCs) to mature erythrocytes are poorly understood. Here, we show that HSPC development to an erythroid-committed proerythroblast...
6.
Clerc I, Abba Moussa D, Vahlas Z, Tardito S, Oburoglu L, Hope T, et al.
Nat Metab
. 2020 May;
1(7):717-730.
PMID: 32373781
The susceptibility of CD4 T cells to human immunodeficiency virus 1 (HIV-1) infection is regulated by glucose and glutamine metabolism, but the relative contributions of these nutrients to infection are...
7.
Resveratrol stimulates the metabolic reprogramming of human CD4 T cells to enhance effector function
Craveiro M, Cretenet G, Mongellaz C, Matias M, Caron O, de Lima M, et al.
Sci Signal
. 2017 Oct;
10(501).
PMID: 29042482
The polyphenol resveratrol activates the deacetylase Sirt1, resulting in various antioxidant, chemoprotectant, neuroprotective, cardioprotective, and anti-inflammatory properties. We found that at high concentrations of resveratrol, human CD4 T cells showed...
8.
Cretenet G, Clerc I, Matias M, Loisel S, Craveiro M, Oburoglu L, et al.
Sci Rep
. 2016 Apr;
6:24129.
PMID: 27067254
CD4 and CD8 T lymphocyte activation requires the generation of sufficient energy to support new biosynthetic demands. Following T cell receptor (TCR) engagement, these requirements are met by an increased...
9.
Klysz D, Tai X, Robert P, Craveiro M, Cretenet G, Oburoglu L, et al.
Sci Signal
. 2015 Oct;
8(396):ra97.
PMID: 26420908
T cell activation requires that the cell meet increased energetic and biosynthetic demands. We showed that exogenous nutrient availability regulated the differentiation of naïve CD4(+) T cells into distinct subsets....
10.
Oburoglu L, Tardito S, Fritz V, de Barros S, Merida P, Craveiro M, et al.
Cell Stem Cell
. 2014 Jun;
15(2):169-84.
PMID: 24953180
The metabolic state of quiescent hematopoietic stem cells (HSCs) is an important regulator of self-renewal, but it is unclear whether or how metabolic parameters contribute to HSC lineage specification and...