Valerie S Zimmermann
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Explore the profile of Valerie S Zimmermann including associated specialties, affiliations and a list of published articles.
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34
Citations
1171
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Recent Articles
1.
Ndjim M, Gasmi I, Herbert F, Josephine C, Bas J, Lamrani A, et al.
Immunity
. 2024 May;
57(6):1260-1273.e7.
PMID: 38744292
Upon parasitic helminth infection, activated intestinal tuft cells secrete interleukin-25 (IL-25), which initiates a type 2 immune response during which lamina propria type 2 innate lymphoid cells (ILC2s) produce IL-13....
2.
Mongellaz C, Vicente R, Noroski L, Noraz N, Courgnaud V, Chinen J, et al.
Front Immunol
. 2023 Jun;
14:1155883.
PMID: 37313400
Introduction: ZAP-70, a protein tyrosine kinase recruited to the T cell receptor (TCR), initiates a TCR signaling cascade upon antigen stimulation. Mutations in the gene cause a combined immunodeficiency characterized...
3.
Calabria A, Cipriani C, Spinozzi G, Rudilosso L, Esposito S, Benedicenti F, et al.
Blood
. 2023 Feb;
141(19):2316-2329.
PMID: 36790505
Adeno-associated virus (AAV) vectors have been successfully exploited in gene therapy applications for the treatment of several genetic disorders. AAV is considered an episomal vector, but it has been shown...
4.
Gonzalez-Menendez P, Phadke I, Olive M, Joly A, Papoin J, Yan H, et al.
Blood
. 2023 Feb;
141(20):2520-2536.
PMID: 36735910
Metabolic programs contribute to hematopoietic stem and progenitor cell (HSPC) fate, but it is not known whether the metabolic regulation of protein synthesis controls HSPC differentiation. Here, we show that...
5.
Phadke I, Pouzolles M, Machado A, Moraly J, Gonzalez-Menendez P, Zimmermann V, et al.
Front Immunol
. 2022 Oct;
13:898827.
PMID: 36248829
Hematopoiesis, a process that results in the differentiation of all blood lineages, is essential throughout life. The production of 1x10 blood cells per day, including 200x10 erythrocytes, is highly dependent...
6.
Babayeva R, Mongellaz C, Karakus I, Cansever M, Bilgic Eltan S, Catak M, et al.
Pediatr Allergy Immunol
. 2022 Mar;
33(3):e13756.
PMID: 35338726
No abstract available.
7.
Matias M, Yong C, Foroushani A, Goldsmith C, Mongellaz C, Sezgin E, et al.
Cell Rep
. 2021 Nov;
37(5):109911.
PMID: 34731632
Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show that cell-permeable α-ketoglutarate (αKG) alters the DNA methylation profile of naive...
8.
Lechner K, Mott S, Al-Saifi R, Knipfer L, Wirtz S, Atreya R, et al.
Gastroenterology
. 2021 Jul;
161(4):1270-1287.e19.
PMID: 34224738
Background & Aims: The molecular checkpoints driving T cell activation and cytokine responses in ulcerative colitis (UC) are incompletely understood. Here, we studied the Tec kinase ITK in UC. Methods:...
9.
Gonzalez-Menendez P, Romano M, Yan H, Deshmukh R, Papoin J, Oburoglu L, et al.
Cell Rep
. 2021 Feb;
34(5):108723.
PMID: 33535038
The metabolic changes controlling the stepwise differentiation of hematopoietic stem and progenitor cells (HSPCs) to mature erythrocytes are poorly understood. Here, we show that HSPC development to an erythroid-committed proerythroblast...
10.
Ishii K, Pouzolles M, Chien C, Erwin-Cohen R, Kohler M, Qin H, et al.
J Clin Invest
. 2020 Sep;
130(10):5425-5443.
PMID: 32925169
Late-onset inflammatory toxicities resembling hemophagocytic lymphohistiocytosis (HLH) or macrophage activation syndrome (MAS) occur after chimeric antigen receptor T cell (CAR T cell) infusion and represent a therapeutic challenge. Given the...