Cedric Gobet
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Explore the profile of Cedric Gobet including associated specialties, affiliations and a list of published articles.
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23
Citations
864
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Recent Articles
1.
Martini T, Gobet C, Salati A, Blanc J, Mookhoek A, Reinehr M, et al.
Nat Commun
. 2024 Sep;
15(1):8422.
PMID: 39341814
Recent single-cell transcriptomes revealed spatiotemporal programmes of liver function on the sublobular scale. However, how sexual dimorphism affected this space-time logic remained poorly understood. We addressed this by performing scRNA-seq...
2.
Delbes A, Quinones M, Gobet C, Castel J, Denis R, Berthelet J, et al.
Sci Adv
. 2023 May;
9(20):eadf2982.
PMID: 37196091
The synchronization of circadian clock depends on a central pacemaker located in the suprachiasmatic nuclei. However, the potential feedback of peripheral signals on the central clock remains poorly characterized. To...
3.
Talamanca L, Gobet C, Naef F
Science
. 2023 Feb;
379(6631):478-483.
PMID: 36730411
The circadian clock modulates human physiology. However, the organization of tissue-specific gene expression rhythms and how these depend on age and sex is not defined in humans. We combined data...
4.
Hurni C, Weger B, Gobet C, Naef F
PLoS Genet
. 2022 Aug;
18(8):e1009903.
PMID: 35921362
In eukaryotes, RNA is synthesised in the nucleus, spliced, and exported to the cytoplasm where it is translated and finally degraded. Any of these steps could be subject to temporal...
5.
Jouffe C, Weger B, Martin E, Atger F, Weger M, Gobet C, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(10):e2200083119.
PMID: 35238641
SignificanceWhile increasing evidence associates the disruption of circadian rhythms with pathologic conditions, including obesity, type 2 diabetes, and nonalcoholic fatty liver diseases (NAFLD), the involved mechanisms are still poorly described....
6.
Gobet C, Naef F
Methods
. 2021 Oct;
203:10-16.
PMID: 34673173
Protein synthesis is an energy consuming process characterised as a pivotal and highly regulated step in gene expression. The net protein output is dictated by a combination of translation initiation,...
7.
Abruzzi K, Gobet C, Naef F, Rosbash M
Science
. 2021 Apr;
372(6539).
PMID: 33859000
Ray (Reports, 14 February 2020, p. 800) recently claimed temperature-compensated, free-running mRNA oscillations in liver slices and skin fibroblasts. We reanalyzed these data and found far fewer reproducible mRNA oscillations...
8.
Weger B, Gobet C, David F, Atger F, Martin E, Phillips N, et al.
Proc Natl Acad Sci U S A
. 2021 Jan;
118(3).
PMID: 33452134
The circadian clock and feeding rhythms are both important regulators of rhythmic gene expression in the liver. To further dissect the respective contributions of feeding and the clock, we analyzed...
9.
Neelagandan N, Lamberti I, Carvalho H, Gobet C, Naef F
Open Biol
. 2020 Dec;
10(12):200292.
PMID: 33292102
Protein synthesis from mRNA is an energy-intensive and tightly controlled cellular process. Translation elongation is a well-coordinated, multifactorial step in translation that undergoes dynamic regulation owing to cellular state and...
10.
Weger M, Weger B, Schink A, Takamiya M, Stegmaier J, Gobet C, et al.
Elife
. 2020 Sep;
9.
PMID: 32969791
The glucose-sensing Mondo pathway regulates expression of metabolic genes in mammals. Here, we characterized its function in the zebrafish and revealed an unexpected role of this pathway in vertebrate embryonic...