Cecilia Wallin
Overview
Explore the profile of Cecilia Wallin including associated specialties, affiliations and a list of published articles.
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17
Citations
288
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Recent Articles
1.
Gallego-Villarejo L, Wallin C, Krol S, Enrich-Bengoa J, Suades A, Aguilella-Arzo M, et al.
Comput Struct Biotechnol J
. 2022 Oct;
20:5672-5679.
PMID: 36284704
Amyloid β-peptide (Aβ) misfolding into β-sheet structures triggers neurotoxicity inducing Alzheimer's disease (AD). Molecules able to reduce or to impair Aβ aggregation are highly relevant as possible AD treatments since...
2.
Wang H, Lallemang M, Hermann B, Wallin C, Loch R, Blanc A, et al.
J Mol Biol
. 2020 Nov;
433(2):166717.
PMID: 33220262
Heat shock protein 90 (Hsp90) is a molecular chaperone that assists protein folding in an Adenosine triphosphate (ATP)-dependent way. Hsp90 has been reported to interact with Alzheimeŕs disease associated amyloid-β...
3.
Wallin C, Jarvet J, Biverstal H, Warmlander S, Danielsson J, Graslund A, et al.
J Biol Chem
. 2020 Apr;
295(21):7224-7234.
PMID: 32241918
A detailed understanding of the molecular pathways for amyloid-β (Aβ) peptide aggregation from monomers into amyloid fibrils, a hallmark of Alzheimer's disease, is crucial for the development of diagnostic and...
4.
Al-Adwani S, Wallin C, Balhuizen M, Veldhuizen E, Coorens M, Landreh M, et al.
Sci Rep
. 2020 Feb;
10(1):2376.
PMID: 32047184
Arginine residues of the antimicrobial peptide LL-37 can be citrullinated by peptidyl arginine deiminases, which reduce the positive charge of the peptide. Notably, citrullinated LL-37 has not yet been detected...
5.
Wallin C, Friedemann M, Sholts S, Noormagi A, Svantesson T, Jarvet J, et al.
Biomolecules
. 2020 Jan;
10(1).
PMID: 31892131
Brains and blood of Alzheimer's disease (AD) patients have shown elevated mercury concentrations, but potential involvement of mercury exposure in AD pathogenesis has not been studied at the molecular level....
6.
Warmlander S, Osterlund N, Wallin C, Wu J, Luo J, Tiiman A, et al.
J Biol Inorg Chem
. 2019 Sep;
24(8):1189-1196.
PMID: 31562546
The amyloid-β (Aβ) peptides are key molecules in Alzheimer's disease (AD) pathology. They interact with cellular membranes, and can bind metal ions outside the membrane. Certain oligomeric Aβ aggregates are...
7.
Pansieri J, Ostojic L, Iashchishyn I, Magzoub M, Wallin C, Warmlander S, et al.
ACS Chem Biol
. 2019 Jun;
14(7):1410-1417.
PMID: 31194501
Amyloid cascade and neuroinflammation are hallmarks of neurodegenerative diseases, and pro-inflammatory S100A9 protein is central to both of them. Here, we have shown that NCAM1 peptide constructs carrying polycationic sequences...
8.
Dong X, Svantesson T, Sholts S, Wallin C, Jarvet J, Graslund A, et al.
Biochem Biophys Res Commun
. 2019 Feb;
510(4):520-524.
PMID: 30737030
Dysregulation and aggregation of the peptide hormone IAPP (islet amyloid polypeptide, a.k.a. amylin) into soluble oligomers that appear to be cell-toxic is a known aspect of diabetes mellitus (DM) Type...
9.
Horvath I, Iashchishyn I, A Moskalenko R, Wang C, Warmlander S, Wallin C, et al.
J Neuroinflammation
. 2018 Jun;
15(1):172.
PMID: 29866153
Background: Chronic neuroinflammation is a hallmark of Parkinson's disease (PD) pathophysiology, associated with increased levels of pro-inflammatory factors in PD brain tissues. The pro-inflammatory mediator and highly amyloidogenic protein S100A9...
10.
Wallin C, Hiruma Y, Warmlander S, Huvent I, Jarvet J, Abrahams J, et al.
J Am Chem Soc
. 2018 May;
140(26):8138-8146.
PMID: 29708745
In Alzheimer's disease, amyloid-β (Aβ) plaques and tau neurofibrillary tangles are the two pathological hallmarks. The co-occurrence and combined reciprocal pathological effects of Aβ and tau protein aggregation have been...