Cathy Slack
Overview
Explore the profile of Cathy Slack including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
1502
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0
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Recent Articles
1.
Guan C, Otchere A, Laskovs M, Papatheodorou I, Slack C
Aging Cell
. 2025 Feb;
:e14500.
PMID: 39943697
Invertebrate models have been instrumental in advancing our understanding of the molecular mechanisms of ageing. The isolation of single gene mutations that both extend lifespan and improve age-related health have...
2.
Prudden H, Tatoud R, Slack C, Shattock R, Anklesaria P, Bekker L, et al.
Vaccines (Basel)
. 2023 May;
11(5).
PMID: 37243074
The development of safe and effective HIV vaccines has been a scientific challenge for more than 40 years. Despite disappointing results from efficacy clinical trials, much has been learnt from...
3.
Mulla S, Ludlam A, Elragig A, Slack C, Balklava Z, Stich M, et al.
R Soc Open Sci
. 2023 Feb;
10(2):220991.
PMID: 36756060
Ageing research focuses on identifying lifespan modifiers and understanding and appropriately interpreting their effects. One of the most relevant quantities being studied is the shape of the survival curve that...
4.
Laskovs M, Partridge L, Slack C
Dis Model Mech
. 2022 Sep;
15(10).
PMID: 36111627
The RAS/MAPK pathway is a highly conserved signalling pathway with a well-established role in cancer. Mutations that hyperactivate this pathway are associated with unregulated cell proliferation. Evidence from a range...
5.
Chen Z, Cordero J, Alqarni A, Slack C, Zeidler M, Bellantuono I
J Gerontol A Biol Sci Med Sci
. 2021 Jun;
77(8):1494-1502.
PMID: 34137822
Over recent decades, increased longevity has not been paralleled by extended health span, resulting in more years spent with multiple diseases in older age. As such, interventions to improve health...
6.
Calimport S, Bentley B, Stewart C, Pawelec G, Scuteri A, Vinciguerra M, et al.
Science
. 2020 May;
368(6491):595-596.
PMID: 32381713
No abstract available.
7.
Wiseman D, Otchere A, Patel J, Uddin R, Pollock N, Routledge S, et al.
Protein Expr Purif
. 2019 Nov;
167:105524.
PMID: 31678667
Given their extensive role in cell signalling, GPCRs are significant drug targets; despite this, many of these receptors have limited or no available prophylaxis. Novel drug design and discovery significantly...
8.
Calimport S, Bentley B, Stewart C, Pawelec G, Scuteri A, Vinciguerra M, et al.
Science
. 2019 Nov;
366(6465):576-578.
PMID: 31672885
No abstract available.
9.
Slack C, Tullet J
Subcell Biochem
. 2019 Feb;
90:323-350.
PMID: 30779014
It is now widely recognised that ageing and its associated functional decline are regulated by a wide range of molecules that fit into specific cellular pathways. Here, we describe several...
10.
Slack C
Nutr Healthy Aging
. 2017 Dec;
4(3):195-205.
PMID: 29276789
Aberrant signal transduction downstream of the Ras GTPase has a well-established role in tumorigenesis. Mutations that result in hyperactivation of Ras are responsible for a third of all human cancers....