Catherine Paradis-Bleau
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Explore the profile of Catherine Paradis-Bleau including associated specialties, affiliations and a list of published articles.
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20
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666
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Recent Articles
1.
Giacomucci S, Alvarez L, Rodrigues C, Cava F, Paradis-Bleau C
Microbiol Spectr
. 2022 Feb;
10(1):e0120321.
PMID: 35170991
While many mechanisms governing bacterial envelope homeostasis have been identified, others remain poorly understood. To decipher these processes, we previously developed an assay in the Gram-negative model Escherichia coli to...
2.
Gravel J, Paradis-Bleau C, Schmitzer A
Medchemcomm
. 2018 Aug;
8(7):1408-1413.
PMID: 30108851
We describe the use of the -nitrophenyl-β-galactoside (ONPG) assay developed by Lehrer to which a new mathematical data treatment was applied. In this simplified assay, only one enzymatic assay is...
3.
Kouidmi I, Alvarez L, Collet J, Cava F, Paradis-Bleau C
J Bacteriol
. 2018 Jul;
200(19).
PMID: 30012727
Peptidoglycan (PG) is the main structural component of bacterial envelopes. It protects bacterial cells against variations in osmotic pressure and cell lysis. The newly discovered factor ElyC has been shown...
4.
Dufresne K, Paradis-Bleau C
Adv Exp Med Biol
. 2015 Dec;
883:41-76.
PMID: 26621461
All free-living bacterial cells are delimited and protected by an envelope of high complexity. This physiological barrier is essential for bacterial survival and assures multiple functions. The molecular assembly of...
5.
Kouidmi I, Levesque R, Paradis-Bleau C
Mol Microbiol
. 2014 Aug;
94(2):242-53.
PMID: 25130693
With antibiotic resistance mechanisms increasing in diversity and spreading among bacterial pathogens, the development of new classes of antibacterial agents against judiciously chosen targets is a high-priority task. The biochemical...
6.
Paradis-Bleau C, Kritikos G, Orlova K, Typas A, Bernhardt T
PLoS Genet
. 2014 Jan;
10(1):e1004056.
PMID: 24391520
The cell envelope of Gram-negative bacteria is a formidable barrier that is difficult for antimicrobial drugs to penetrate. Thus, the list of treatments effective against these organisms is small and...
7.
Paradis-Bleau C, Markovski M, Uehara T, Lupoli T, Walker S, Kahne D, et al.
Cell
. 2010 Dec;
143(7):1110-20.
PMID: 21183074
Most bacteria surround themselves with a peptidoglycan (PG) exoskeleton synthesized by polysaccharide polymerases called penicillin-binding proteins (PBPs). Because they are the targets of penicillin and related antibiotics, the structure and...
8.
Gadjeva M, Paradis-Bleau C, Priebe G, Fichorova R, Pier G
J Immunol
. 2009 Dec;
184(1):296-302.
PMID: 19949109
The inflammatory response to Pseudomonas aeruginosa is not properly regulated in the lungs of patients with cystic fibrosis (CF). In the lung epithelium of individuals with wild-type CF transmembrane conductance...
9.
Cloutier I, Paradis-Bleau C, Giroux A, Pigeon X, Arseneault M, Levesque R, et al.
Eur Biophys J
. 2009 Aug;
39(2):263-76.
PMID: 19669132
The use of naturally occurring lytic bacteriophage proteins as specific antibacterial agents is a promising way to treat bacterial infections caused by antibiotic-resistant pathogens. The opportunity to develop bacterial resistance...
10.
Paradis-Bleau C, Lloyd A, Sanschagrin F, Maaroufi H, Clarke T, Blewett A, et al.
Biochem J
. 2009 Apr;
421(2):263-72.
PMID: 19400768
The enzyme kinetics of the amide ligase MurE, a cell wall biosynthesis enzyme, from Pseudomonas aeruginosa were determined using the synthesized nucleotide substrate UDP-MurNAc-Ala-Glu (uridine 5'-diphosphoryl N-acetylmuramoyl-L-alanyl-D-glutamate). When coupled to...