Catherine Paradis-Bleau
Overview
Explore the profile of Catherine Paradis-Bleau including associated specialties, affiliations and a list of published articles.
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20
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666
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Recent Articles
11.
Paradis-Bleau C, Lloyd A, Sanschagrin F, Clarke T, Blewett A, Bugg T, et al.
BMC Biochem
. 2008 Dec;
9:33.
PMID: 19099588
Background: To develop antibacterial agents having novel modes of action against bacterial cell wall biosynthesis, we targeted the essential MurF enzyme of the antibiotic resistant pathogen Pseudomonas aeruginosa. MurF catalyzes...
12.
Winstanley C, Langille M, Fothergill J, Kukavica-Ibrulj I, Paradis-Bleau C, Sanschagrin F, et al.
Genome Res
. 2008 Dec;
19(1):12-23.
PMID: 19047519
Pseudomonas aeruginosa isolates have a highly conserved core genome representing up to 90% of the total genomic sequence with additional variable accessory genes, many of which are found in genomic...
13.
Campodonico V, Gadjeva M, Paradis-Bleau C, Uluer A, Pier G
Trends Mol Med
. 2008 Feb;
14(3):120-33.
PMID: 18262467
Defective expression or function of the cystic fibrosis transmembrane conductance regulator (CFTR) underlies the hypersusceptibility of cystic fibrosis (CF) patients to chronic airway infections, particularly with Pseudomonas aeruginosa. CFTR is...
14.
Taha M, Atallah N, Al-Bakri A, Paradis-Bleau C, Zalloum H, Younis K, et al.
Bioorg Med Chem
. 2007 Nov;
16(3):1218-35.
PMID: 17988876
The pharmacophoric space of streptococcal MurF was explored using a set of 39 known inhibitors. Subsequently, genetic algorithm and multiple linear regression analysis were employed to select an optimal combination...
15.
Paradis-Bleau C, Cloutier I, Lemieux L, Sanschagrin F, Laroche J, Auger M, et al.
FEMS Microbiol Lett
. 2007 Jan;
266(2):201-9.
PMID: 17233731
The gp144 endolysin gene from the Pseudomonas aeruginosa phage phiKZ was cloned and studies of gp144 expression into Escherichia coli showed host cell lysis. The gp144 protein was purified directly...
16.
Paradis-Bleau C, Beaumont M, Sanschagrin F, Voyer N, Levesque R
Bioorg Med Chem
. 2006 Dec;
15(3):1330-40.
PMID: 17157508
As a model system for designing new inhibitors of bacterial cell division, we studied the essential and highly conserved FtsZ GTPase from Pseudomonas aeruginosa. A collection of GTP analogues were...
17.
Paradis-Bleau C, Beaumont M, Boudreault L, Lloyd A, Sanschagrin F, Bugg T, et al.
Peptides
. 2006 Mar;
27(7):1693-700.
PMID: 16517013
The purified Pseudomonas aeruginosa cell wall biosynthesis MurD amide ligase enzyme was used to screen C-7-C and 12 mers peptides from phage display libraries using competitive biopanning approaches with the...
18.
Paradis-Bleau C, Sanschagrin F, Levesque R
Protein Eng Des Sel
. 2005 Mar;
18(2):85-91.
PMID: 15790573
The revolutionary era of antibiotics has been overwhelmed by the evolutionary capacity of microorganisms such as Pseudomonas aeruginosa to develop resistance to all classes of antibiotics. In the perspective of...
19.
Paradis-Bleau C, Sanschagrin F, Levesque R
J Antimicrob Chemother
. 2004 Jun;
54(1):278-80.
PMID: 15190020
No abstract available.
20.
Diarra M, Lacasse P, Deschenes E, Grondin G, Paradis-Bleau C, Petitclerc D
J Electron Microsc (Tokyo)
. 2003 Jul;
52(2):207-15.
PMID: 12868591
To investigate the effect of lactoferrin or lactoferricin with or without penicillin G, light and transmission electron microscopy were performed on thin sections of two Staphylococcus aureus strains. Lactoferrin affected...