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Catherine F Hughes

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Citations 504
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Recent Articles
1.
Lyons O, Kerr M, Flynn M, Hoey L, Hughes C, Caffrey A, et al.
Diabetol Metab Syndr . 2024 Jun; 16(1):125. PMID: 38849940
Background: Nutrition is recognized as playing an important role in the metabolic syndrome (MetS), but the dietary components involved are unclear. We aimed to investigate nutrition factors in relation to...
2.
Fitzpatrick D, Laird E, Ward M, Hoey L, Hughes C, Strain J, et al.
Bone . 2024 Apr; 184:117108. PMID: 38642819
Introduction: Secondary hyperparathyroidism (SHPT) has adverse implications for bone health but is relatively understudied. In this study we examine the prevalence and determinants of SHPT and describe the relationship of...
3.
Dyer A, McNulty H, Caffrey A, Gordon S, Laird E, Hoey L, et al.
Neurobiol Aging . 2023 Dec; 134:94-105. PMID: 38043161
Studies examining the relationships between chronic inflammation, cognitive function and cognitive decline in older adults have yielded conflicting results. In a large cohort of older adults free from established dementia...
4.
Fitzpatrick D, Lannon R, Laird E, Ward M, Hoey L, Hughes C, et al.
Osteoporos Int . 2023 Aug; 34(11):1917-1926. PMID: 37530847
Purpose: Proton pump inhibitors (PPIs) are associated with increased risk of osteoporotic fracture. Hyperparathyroidism may be implicated, but few studies have considered this relationship. This study evaluated the relationship between...
5.
Jarrett H, McNulty H, Hughes C, Pentieva K, Strain J, McCann A, et al.
Am J Clin Nutr . 2022 Oct; 116(6):1767-1778. PMID: 36264281
Background: The generation of the active form of vitamin B-6, pyridoxal 5'-phosphate (PLP), in tissues is dependent upon riboflavin as flavin mononucleotide, but whether this interaction is important for maintaining...
6.
Clements M, Heffernan M, Ward M, Hoey L, Doherty L, Mendes R, et al.
J Bone Miner Res . 2022 Sep; 37(12):2443-2455. PMID: 36128889
Folate, vitamins B12, B6, and riboflavin are required for one-carbon metabolism and may affect bone health, but no previous randomized trial has investigated all four nutrients in this context. We...
7.
Rooney M, Hughes C, Strain J, Clements M, McNulty H, Ward M
J Hum Nutr Diet . 2022 Jul; 35(4):689-700. PMID: 35821207
Background: The C677T polymorphism in the gene-encoding methylenetetrahydrofolate reductase (MTHFR) is associated with an increased risk of hypertension and cardiovascular disease. Riboflavin, the MTHFR cofactor, is an important modulator of...
8.
Dyer A, Laird E, Hoey L, Hughes C, McNulty H, Ward M, et al.
Int J Geriatr Psychiatry . 2022 Jun; 37(7). PMID: 35719039
Objectives: Whilst chronic kidney disease has been associated with cognitive impairment, the association between reduced estimated Glomerular Filtration Rate (eGFR) and domain-specific cognitive performance is less clear and may represent...
9.
Dyer A, Briggs R, Laird E, Hoey L, Hughes C, McNulty H, et al.
Diabet Med . 2021 Aug; 38(11):e14668. PMID: 34343367
Aims: Given that diabetes is associated with cognitive impairment and dementia in later life, we aimed to investigate the relationship between glycated haemoglobin (HbA ), diabetes and domain-specific neuropsychological performance...
10.
Dyer A, Laird E, Hoey L, Hughes C, McNulty H, Ward M, et al.
Int J Geriatr Psychiatry . 2021 Jul; 36(11):1767-1777. PMID: 34227695
Background: Long-term use of anticholinergics, benzodiazepines and related drugs (or "Z-drugs") have been associated with cognitive impairment and dementia. However, the relationship of these medications with cognitive function and domain-specific...