Catherine E Braine
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Explore the profile of Catherine E Braine including associated specialties, affiliations and a list of published articles.
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8
Citations
319
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Recent Articles
1.
Harder J, Williams P, Braine C, Yang H, Thomas J, Foxworth N, et al.
J Neuroinflammation
. 2020 Nov;
17(1):336.
PMID: 33176797
Background: The risk of glaucoma increases significantly with age and exposure to elevated intraocular pressure, two factors linked with neuroinflammation. The complement cascade is a complex immune process with many...
2.
Williams P, Braine C, Kizhatil K, Foxworth N, Tolman N, Harder J, et al.
Mol Neurodegener
. 2019 Jan;
14(1):6.
PMID: 30670050
Background: Glaucoma is characterized by the progressive dysfunction and loss of retinal ganglion cells. Recent work in animal models suggests that a critical neuroinflammatory event damages retinal ganglion cell axons...
3.
Harder J, Braine C, Williams P, Zhu X, MacNicoll K, Sousa G, et al.
Proc Natl Acad Sci U S A
. 2017 Apr;
114(19):E3839-E3848.
PMID: 28446616
Various immune response pathways are altered during early, predegenerative stages of glaucoma; however, whether the early immune responses occur secondarily to or independently of neuronal dysfunction is unclear. To investigate...
4.
Williams P, Braine C, Foxworth N, Cochran K, John S
J Neuroinflammation
. 2017 Apr;
14(1):93.
PMID: 28446179
Background: We previously reported a profound long-term neuroprotection subsequent to a single radiation-therapy in the DBA/2J mouse model of glaucoma. This neuroprotection prevents entry of monocyte-like immune cells into the...
5.
Tseng H, Riday T, McKee C, Braine C, Bomze H, Barak I, et al.
Neurobiol Aging
. 2015 Mar;
36(6):2201-12.
PMID: 25818176
Primary open-angle glaucoma (POAG) is characterized by progressive neurodegeneration of retinal ganglion cells (RGCs). Why RGCs degenerate in low-pressure POAG remains poorly understood. To gain mechanistic insights, we developed a...
6.
Lee S, Williams P, Braine C, Lin D, John S, Irazoqui P
IEEE Trans Neural Syst Rehabil Eng
. 2015 Jan;
23(4):655-64.
PMID: 25608307
Controlled, wireless neuromodulation using miniature implantable devices is a long-sought goal in neuroscience. It will allow many studies and treatments that are otherwise impractical. Recent studies demonstrate advances in neuromodulation...
7.
Howell G, MacNicoll K, Braine C, Soto I, Macalinao D, Sousa G, et al.
Neurobiol Dis
. 2014 Aug;
71:44-52.
PMID: 25132557
The endothelin system is implicated in various human and animal glaucomas. Targeting the endothelin system has great promise as a treatment for human glaucoma, but the cell types involved and...
8.
Williams P, Howell G, Barbay J, Braine C, Sousa G, John S, et al.
PLoS One
. 2013 Aug;
8(8):e72282.
PMID: 23977271
Glaucoma is a complex disease affecting an estimated 70 million people worldwide, characterised by the progressive degeneration of retinal ganglion cells and accompanying visual field loss. The common site of...