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Catherine Demos

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Citations 52
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Recent Articles
1.
Ashton N, Keshavan A, Brum W, Andreasson U, Arslan B, Droescher M, et al.
Alzheimers Dement . 2025 Feb; 21(2):e14508. PMID: 39907496
Introduction: The Alzheimer's Association Global Biomarker Standardization Consortium conducted a blinded case-control study to learn which phosphorylated tau (p-tau) assays provide the largest fold-changes in Alzheimer's disease (AD) versus non-AD...
2.
Ashton N, Keshavan A, Brum W, Andreasson U, Arslan B, Droescher M, et al.
medRxiv . 2024 Sep; PMID: 39228740
Background: Phosphorylated tau (p-tau) is a specific blood biomarker for Alzheimer's disease (AD) pathology. Multiple p-tau biomarkers on several analytical platforms are poised for clinical use. The Alzheimer's Association Global...
3.
Chatanaka M, Avery L, Pasic M, Sithravadivel S, Rotstein D, Demos C, et al.
Clin Proteomics . 2024 Apr; 21(1):28. PMID: 38580905
Background: Certain demyelinating disorders, such as neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) exhibit serum autoantibodies against aquaporin-4 (αAQP4) and myelin oligodendrocyte glycoprotein (αMOG). The...
4.
Kivisakk P, Fatima H, Cahoon D, Otieno B, Chacko L, Minooei F, et al.
Sci Rep . 2024 Jan; 14(1):629. PMID: 38182740
A growing literature suggests that plasma levels of tau phosphorylated at amino acid 217 (pTau217) performs similarly to cerebrospinal fluid (CSF) biomarkers and PET imaging to detect amyloid pathology and...
5.
Tamargo I, In Baek K, Xu C, Kang D, Kim Y, Andueza A, et al.
Circulation . 2023 Dec; 149(15):1183-1201. PMID: 38099436
Background: Atherosclerosis preferentially occurs in arterial regions of disturbed blood flow, and stable flow (s-flow) protects against atherosclerosis by incompletely understood mechanisms. Methods: Our single-cell RNA-sequencing data using the mouse...
6.
Chatanaka M, Avery L, Pasic M, Sithravadivel S, Rotstein D, Demos C, et al.
Res Sq . 2023 Dec; PMID: 38077014
Background: Certain demyelinating disorders, such as neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) exhibit serum autoantibodies against aquaporin-4 (αAQP4) and myelin oligodendrocyte glycoprotein (αMOG). The...
7.
Demos C, Johnson J, Andueza A, Park C, Kim Y, Villa-Roel N, et al.
Front Cardiovasc Med . 2022 Oct; 9():979745. PMID: 36247423
Atherosclerosis is a chronic inflammatory disease and occurs preferentially in arterial regions exposed to disturbed blood flow (d-flow) while the stable flow (s-flow) regions are spared. D-flow induces endothelial inflammation...
8.
Lassegue B, Kumar S, Mandavilli R, Wang K, Tsai M, Kang D, et al.
PLoS One . 2021 Dec; 16(12):e0247261. PMID: 34928942
POLDIP2 is a multifunctional protein whose roles are only partially understood. Our laboratory previously reported physiological studies performed using a mouse gene trap model, which suffered from three limitations: perinatal...
9.
Kumar S, Sur S, Perez J, Demos C, Kang D, Kim C, et al.
Curr Top Membr . 2021 Oct; 87():97-130. PMID: 34696890
Hypercholesterolemia is a well-known pro-atherogenic risk factor and statin is the most effective anti-atherogenic drug that lowers blood cholesterol levels. However, despite systemic hypercholesterolemia, atherosclerosis preferentially occurs in arterial regions...
10.
Dosta P, Demos C, Ramos V, Kang D, Kumar S, Jo H, et al.
Cardiovasc Eng Technol . 2021 Jan; 12(1):114-125. PMID: 33474643
Purpose: Endothelial cell (EC) dysfunction underlies the pathology of multiple disease conditions including cardiovascular and pulmonary diseases. Dysfunctional ECs have a distinctive gene expression profile compared to healthy ECs. RNAi...