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Kaj Blennow

Explore the profile of Kaj Blennow including associated specialties, affiliations and a list of published articles. Areas
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Articles 1893
Citations 83627
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Recent Articles
1.
Knorr U, Simonsen A, Nilsson J, Brinkmalm A, Zetterberg H, Blennow K, et al.
J Psychiatr Res . 2025 Mar; 184:288-296. PMID: 40081262
This study is the first to investigate the association between a comprehensive panel of cerebrospinal fluid (CSF) synaptic protein biomarkers and cognitive function using data from a prospective cohort study...
2.
Xu X, Kwon J, Yan R, Apio C, Song S, Heo G, et al.
JAMA Netw Open . 2025 Mar; 8(3):e250562. PMID: 40067298
Importance: Age, sex, and apolipoprotein E (APOE) are the strongest risk factors for late-onset Alzheimer disease (AD). The role of APOE in AD varies with sex and ancestry. While the...
3.
Zhang H, Kargilis D, Tropea T, Robinson J, Shen J, Brody E, et al.
Ann Clin Transl Neurol . 2025 Mar; PMID: 40053464
Objective: Several genetic loci known to confer risk for Parkinson's disease (PD) function in lysosomal pathways. We systematically screened common variants linked to PD risk by genome-wide association studies (GWAS)...
4.
Alpaugh M, Lantero-Rodriguez J, Benedet A, Manseau U, Boutin M, Maiuri M, et al.
J Neurol . 2025 Mar; 272(3):254. PMID: 40047995
Tau is a microtubule protein that is known to be hyperphosphorylated and to aggregate in several chronic neurodegenerative disorders. In many cases, in particular in Alzheimer's disease, the degree of...
5.
Kim S, Shin D, Ham H, Kim Y, Gu Y, Kim H, et al.
JAMA Netw Open . 2025 Mar; 8(3):e250096. PMID: 40042844
Importance: Physical activity (PA) is a nonpharmacological intervention for dementia prevention. The association between PA and Alzheimer disease (AD) plasma biomarkers remains underexplored. Objective: To investigate the associations among PA;...
6.
Leuzy A, Bollack A, Pellegrino D, Teunissen C, La Joie R, Rabinovici G, et al.
Alzheimers Dement . 2025 Mar; 21(3):e14528. PMID: 40042435
Amyloid-β (Aβ) positron emission tomography (PET) imaging and cerebrospinal fluid (CSF) biomarkers are now established tools in the diagnostic workup of patients with Alzheimer's disease (AD), and their use is...
7.
Lennol M, Garcia-Ayllon M, Aviles-Granados C, Trasciatti C, Tolassi C, Quaresima V, et al.
J Infect Dis . 2025 Mar; PMID: 40036349
Background: This study assesses the cerebrospinal fluid (CSF) levels of the viral receptor angiotensin-converting enzyme 2 (ACE2) and of the serine protease TMPRSS2 fragments in patients with SARS-CoV-2 infection presenting...
8.
Hicks A, Plourde J, Selmanovic E, de Souza N, Blennow K, Zetterberg H, et al.
medRxiv . 2025 Mar; PMID: 40034765
Blood-based protein biomarkers may provide important insights into the long-term neuropathology of traumatic brain injury (TBI). This is urgently required to identify mechanistic processes underlying post-traumatic neurodegeneration (PTND); a progressive...
9.
Wesenhagen K, de Leeuw D, Tomassen J, Gobom J, Bos I, Vos S, et al.
Alzheimers Res Ther . 2025 Mar; 17(1):56. PMID: 40033427
Background: We investigated how cerebrospinal fluid levels of synaptic proteins associate with memory function in normal cognition (CN) and mild cognitive impairment (MCI), and investigated the effect of amyloid positivity...
10.
Abughofah Y, Deardorff R, Vosmeier A, Hottle S, Dage J, Dempsey D, et al.
Alzheimers Dement (Amst) . 2025 Feb; 17(1):e70094. PMID: 40018325
Introduction: The brain age gap estimation (BrainAGE) method uses a machine learning model to generate an age estimate from structural magnetic resonance imaging (MRI) scans. The goal was to study...