Aftab Nadeem
Overview
Explore the profile of Aftab Nadeem including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
322
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Recent Articles
1.
Yabrag A, Ullah N, Baryalai P, Ahmad I, Zlatkov N, Toh E, et al.
Cell Death Discov
. 2025 Feb;
11(1):66.
PMID: 39971918
Pore-forming toxins (PFTs) are recognized as major virulence factors produced by both Gram-positive and Gram-negative bacteria. While the effects of PFTs have been extensively investigated using mammalian cells as a...
2.
Bodra N, Toh E, Nadeem A, Nyunt Wai S, Persson K
Front Microbiol
. 2024 Oct;
15:1457850.
PMID: 39421563
Pathogenic serotypes of , transmitted through contaminated water and food, are responsible for outbreaks of cholera, an acute diarrheal disease. While the cholera toxin is the primary virulence factor, also...
3.
Mushtaq F, Nadeem A, Yabrag A, Bala A, Karah N, Zlatkov N, et al.
Microbiol Spectr
. 2024 Jan;
12(2):e0295623.
PMID: 38205963
Carbapenem-resistant causes one of the most difficult-to-treat nosocomial infections. Polycationic drugs like polymyxin B or colistin and tetracycline drugs such as doxycycline or minocycline are commonly used to treat infections...
4.
Ahmad I, Nadeem A, Mushtaq F, Zlatkov N, Shahzad M, Zavialov A, et al.
NPJ Biofilms Microbiomes
. 2023 Dec;
9(1):101.
PMID: 38097635
Acinetobacter baumannii has emerged as one of the most common extensive drug-resistant nosocomial bacterial pathogens. Not only can the bacteria survive in hospital settings for long periods, but they are...
5.
Farag S, Francis M, Gurung J, Nyunt Wai S, Stenlund H, Francis M, et al.
Virulence
. 2023 Aug;
14(1):2249790.
PMID: 37621095
Translocon pores formed in the eukaryotic cell membrane by a type III secretion system facilitate the translocation of immune-modulatory effector proteins into the host cell interior. The YopB and YopD...
6.
Schmidtchen A, Mirza H, van der Plas M, Nadeem A, Puthia M
Front Pharmacol
. 2022 Dec;
13:1108263.
PMID: 36578538
No abstract available.
7.
Toh E, Baryalai P, Nadeem A, Aung K, Chen S, Persson K, et al.
Cell Death Dis
. 2022 Dec;
13(12):1024.
PMID: 36473840
Recently, we demonstrated that a novel bacterial cytotoxin, the protein MakA which is released by Vibrio cholerae, is a virulence factor, causing killing of Caenorhabditis elegans when the worms are...
8.
Liu Y, Nadeem A, Sebastian S, Olsson M, Wai S, Styring E, et al.
Mater Today Bio
. 2022 Mar;
14:100227.
PMID: 35265825
Efficient systemic pharmacological treatment of solid tumors is hampered by inadequate tumor concentration of cytostatics necessitating development of smart local drug delivery systems. To overcome this, we demonstrate that doxorubicin...
9.
Nadeem A, Berg A, Pace H, Alam A, Toh E, Aden J, et al.
Elife
. 2022 Feb;
11.
PMID: 35131030
The α-pore-forming toxins (α-PFTs) from pathogenic bacteria damage host cell membranes by pore formation. We demonstrate a remarkable, hitherto unknown mechanism by an α-PFT protein from . As part of...
10.
Hansen F, Nadeem A, Browning K, Campana M, Schmidtchen A, van der Plas M
J Innate Immun
. 2021 Dec;
14(5):418-432.
PMID: 34937021
Proteolytic cleavage of thrombin generates C-terminal host defense peptides exerting multiple immunomodulatory effects in response to bacterial stimuli. Previously, we reported that thrombin-derived C-terminal peptides (TCPs) are internalized in monocytes...